2bks: Difference between revisions

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[[Image:2bks.gif|left|200px]]<br /><applet load="2bks" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2bks.gif|left|200px]]
caption="2bks, resolution 2.2&Aring;" />
 
'''CRYSTAL STRUCTURE OF RENIN-PF00074777 COMPLEX'''<br />
{{Structure
|PDB= 2bks |SIZE=350|CAPTION= <scene name='initialview01'>2bks</scene>, resolution 2.2&Aring;
|SITE= <scene name='pdbsite=AC1:Pz1+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=PZ1:(6R)-6-({[1-(3-HYDROXYPROPYL)-1,7-DIHYDROQUINOLIN-7-YL]OXY}METHYL)-1-(4-{3-[(2-METHOXYBENZYL)OXY]PROPOXY}PHENYL)PIPERAZIN-2-ONE'>PZ1</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF RENIN-PF00074777 COMPLEX'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2BKS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PZ1:'>PZ1</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Renin Renin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.15 3.4.23.15] Known structural/functional Site: <scene name='pdbsite=AC1:Pz1+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKS OCA].  
2BKS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BKS OCA].  


==Reference==
==Reference==
Equipotent activity in both enantiomers of a series of ketopiperazine-based renin inhibitors., Powell NA, Clay EH, Holsworth DD, Bryant JW, Ryan MJ, Jalaie M, Zhang E, Edmunds JJ, Bioorg Med Chem Lett. 2005 May 2;15(9):2371-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15837327 15837327]
Equipotent activity in both enantiomers of a series of ketopiperazine-based renin inhibitors., Powell NA, Clay EH, Holsworth DD, Bryant JW, Ryan MJ, Jalaie M, Zhang E, Edmunds JJ, Bioorg Med Chem Lett. 2005 May 2;15(9):2371-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15837327 15837327]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Renin]]
[[Category: Renin]]
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[[Category: zymogen]]
[[Category: zymogen]]


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