4cwf: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4cwf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CWF FirstGlance]. <br> | <table><tr><td colspan='2'>[[4cwf]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CWF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4CWF FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H05:5-PROPYL[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-2-AMINE'>H05</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=H05:5-PROPYL[1,2,4]TRIAZOLO[1,5-C]QUINAZOLIN-2-AMINE'>H05</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cwn|4cwn]], [[4cwo|4cwo]], [[4cwp|4cwp]], [[4cwq|4cwq]], [[4cwr|4cwr]], [[4cws|4cws]], [[4cwt|4cwt]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4cwn|4cwn]], [[4cwo|4cwo]], [[4cwp|4cwp]], [[4cwq|4cwq]], [[4cwr|4cwr]], [[4cws|4cws]], [[4cwt|4cwt]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cwf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cwf RCSB], [http://www.ebi.ac.uk/pdbsum/4cwf PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4cwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4cwf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4cwf RCSB], [http://www.ebi.ac.uk/pdbsum/4cwf PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/HS90A_HUMAN HS90A_HUMAN]] Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.<ref>PMID:15937123</ref> <ref>PMID:11274138</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Amboldi, N | [[Category: Amboldi, N]] | ||
[[Category: Brasca, G | [[Category: Brasca, G]] | ||
[[Category: Caronni, D | [[Category: Caronni, D]] | ||
[[Category: Casale, E | [[Category: Casale, E]] | ||
[[Category: Casuscelli, F | [[Category: Casuscelli, F]] | ||
[[Category: Colombo, N | [[Category: Colombo, N]] | ||
[[Category: Dalvit, C | [[Category: Dalvit, C]] | ||
[[Category: Felder, E R | [[Category: Felder, E R]] | ||
[[Category: Fogliatto, G | [[Category: Fogliatto, G]] | ||
[[Category: Isacchi, A | [[Category: Isacchi, A]] | ||
[[Category: Mantegani, S | [[Category: Mantegani, S]] | ||
[[Category: Polucci, P | [[Category: Polucci, P]] | ||
[[Category: Riceputi, L | [[Category: Riceputi, L]] | ||
[[Category: Sola, F | [[Category: Sola, F]] | ||
[[Category: Visco, C | [[Category: Visco, C]] | ||
[[Category: Zuccotto, F | [[Category: Zuccotto, F]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||