4kg8: Difference between revisions
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==Crystal structure of light mutant== | |||
=== | <StructureSection load='4kg8' size='340' side='right' caption='[[4kg8]], [[Resolution|resolution]] 2.25Å' scene=''> | ||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[4kg8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KG8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KG8 FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4en0|4en0]], [[4j6g|4j6g]], [[4fhq|4fhq]], [[3k51|3k51]], [[3mi8|3mi8]], [[3mhd|3mhd]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TNFSF14, HVEML, LIGHT, UNQ391/PRO726 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kg8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kg8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kg8 RCSB], [http://www.ebi.ac.uk/pdbsum/4kg8 PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TNF14_HUMAN TNF14_HUMAN]] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. | [[http://www.uniprot.org/uniprot/TNF14_HUMAN TNF14_HUMAN]] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Almo, S C | [[Category: Almo, S C]] | ||
[[Category: Bonanno, J B | [[Category: Bonanno, J B]] | ||
[[Category: IFN, Atoms-to-Animals:.The Immune Function Network | [[Category: IFN, Atoms-to-Animals:.The Immune Function Network]] | ||
[[Category: Kumar, P R | [[Category: Kumar, P R]] | ||
[[Category: Liu, W | [[Category: Liu, W]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Nathenson, S G | [[Category: Nathenson, S G]] | ||
[[Category: Zhan, C | [[Category: Zhan, C]] | ||
[[Category: Atoms-to-animals: the immune function network]] | [[Category: Atoms-to-animals: the immune function network]] | ||
[[Category: Bind tnf receptor hvem and ltbr]] | [[Category: Bind tnf receptor hvem and ltbr]] | ||
| Line 27: | Line 31: | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: N-glycosylation]] | [[Category: N-glycosylation]] | ||
[[Category: Nysgrc]] | [[Category: Nysgrc]] | ||
[[Category: Protein structure initiative]] | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Psi-biology]] | [[Category: Psi-biology]] | ||
[[Category: Secreted protein]] | [[Category: Secreted protein]] | ||
[[Category: Tnf superfamily]] | [[Category: Tnf superfamily]] | ||
Revision as of 06:21, 25 December 2014
Crystal structure of light mutantCrystal structure of light mutant
Structural highlights
Function[TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. |
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Homo sapiens
- Almo, S C
- Bonanno, J B
- IFN, Atoms-to-Animals:.The Immune Function Network
- Kumar, P R
- Liu, W
- Structural genomic
- Nathenson, S G
- Zhan, C
- Atoms-to-animals: the immune function network
- Bind tnf receptor hvem and ltbr
- Cytokine
- Dcr3
- Hvem
- Ifn
- Immunity
- Jelly-roll fold
- Ltbr
- Membrane
- N-glycosylation
- Nysgrc
- PSI, Protein structure initiative
- Psi-biology
- Secreted protein
- Tnf superfamily