3w2h: Difference between revisions
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<StructureSection load='3w2h' size='340' side='right' caption='[[3w2h]], [[Resolution|resolution]] 1.75Å' scene=''> | <StructureSection load='3w2h' size='340' side='right' caption='[[3w2h]], [[Resolution|resolution]] 1.75Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3w2h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2H OCA]. <br> | <table><tr><td colspan='2'>[[3w2h]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W2H OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W2H FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ndh|1ndh]], [[3w2e|3w2e]], [[3w2f|3w2f]], [[3w2g|3w2g]], [[3w2i|3w2i]], [[3w5h|3w5h]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ndh|1ndh]], [[3w2e|3w2e]], [[3w2f|3w2f]], [[3w2g|3w2g]], [[3w2i|3w2i]], [[3w5h|3w5h]]</td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYB5R3, DIA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CYB5R3, DIA1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9823 PIG])</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cytochrome-b5_reductase Cytochrome-b5 reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.2.2 1.6.2.2] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w2h RCSB], [http://www.ebi.ac.uk/pdbsum/3w2h PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w2h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w2h OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w2h RCSB], [http://www.ebi.ac.uk/pdbsum/3w2h PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/NB5R3_PIG NB5R3_PIG]] Desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism, and, in erythrocyte, methemoglobin reduction.[:] | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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Elucidations of the catalytic cycle of NADH-cytochrome b5 reductase by X-ray crystallography: new insights into regulation of efficient electron transfer.,Yamada M, Tamada T, Takeda K, Matsumoto F, Ohno H, Kosugi M, Takaba K, Shoyama Y, Kimura S, Kuroki R, Miki K J Mol Biol. 2013 Nov 15;425(22):4295-306. doi: 10.1016/j.jmb.2013.06.010. Epub, 2013 Jul 2. PMID:23831226<ref>PMID:23831226</ref> | Elucidations of the catalytic cycle of NADH-cytochrome b5 reductase by X-ray crystallography: new insights into regulation of efficient electron transfer.,Yamada M, Tamada T, Takeda K, Matsumoto F, Ohno H, Kosugi M, Takaba K, Shoyama Y, Kimura S, Kuroki R, Miki K J Mol Biol. 2013 Nov 15;425(22):4295-306. doi: 10.1016/j.jmb.2013.06.010. Epub, 2013 Jul 2. PMID:23831226<ref>PMID:23831226</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||
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[[Category: Cytochrome-b5 reductase]] | [[Category: Cytochrome-b5 reductase]] | ||
[[Category: Pig]] | [[Category: Pig]] | ||
[[Category: Kimura, S | [[Category: Kimura, S]] | ||
[[Category: Kuroki, R | [[Category: Kuroki, R]] | ||
[[Category: Matsumoto, F | [[Category: Matsumoto, F]] | ||
[[Category: Miki, K | [[Category: Miki, K]] | ||
[[Category: Shoyama, Y | [[Category: Shoyama, Y]] | ||
[[Category: Tamada, T | [[Category: Tamada, T]] | ||
[[Category: Yamada, M | [[Category: Yamada, M]] | ||
[[Category: Cytochrome b5]] | [[Category: Cytochrome b5]] | ||
[[Category: Oxidoreductase]] | [[Category: Oxidoreductase]] | ||
[[Category: Reductase]] | [[Category: Reductase]] | ||