2an5: Difference between revisions

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-[[Image:2an5.gif|left|200px]]<br /><applet load="2an5" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2an5.gif|left|200px]]
-caption="2an5, resolution 2.500&Aring;" />
-'''Structure of human PNMT complexed with S-adenosyl-homocysteine and an inhibitor, trans-(1S,2S)-2-amino-1-tetralol'''<br />
+ {{Structure
+|PDB= 2an5 |SIZE=350|CAPTION= <scene name='initialview01'>2an5</scene>, resolution 2.500&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene> and <scene name='pdbligand=TTL:TRANS-(1S,2S)-2-AMINO-1,2,3,4-TETRAHYDRONAPHTHALEN-1-OL'>TTL</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Phenylethanolamine_N-methyltransferase Phenylethanolamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.28 2.1.1.28]
+|GENE= PNMT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Structure of human PNMT complexed with S-adenosyl-homocysteine and an inhibitor, trans-(1S,2S)-2-amino-1-tetralol'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-AN5 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=SAH:'>SAH</scene> and <scene name='pdbligand=TTL:'>TTL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Phenylethanolamine_N-methyltransferase Phenylethanolamine N-methyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.28 2.1.1.28] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN5 OCA].
+AN5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AN5 OCA].
 ==Reference==
-Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis., Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL, Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16363801 16363801]
+Mode of binding of methyl acceptor substrates to the adrenaline-synthesizing enzyme phenylethanolamine N-methyltransferase: implications for catalysis., Gee CL, Tyndall JD, Grunewald GL, Wu Q, McLeish MJ, Martin JL, Biochemistry. 2005 Dec 27;44(51):16875-85. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16363801 16363801]
 [[Category: Homo sapiens]]
 [[Category: Phenylethanolamine N-methyltransferase]]
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 [[Category: s-adenosyl-l-methionine]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:28:58 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:51:34 2008''