2ajd: Difference between revisions

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[[Image:2ajd.gif|left|200px]]<br /><applet load="2ajd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ajd.gif|left|200px]]
caption="2ajd, resolution 2.560&Aring;" />
 
'''Porcine dipeptidyl peptidase IV (CD26) in complex with L-Pro-boro-L-Pro (boroPro)'''<br />
{{Structure
|PDB= 2ajd |SIZE=350|CAPTION= <scene name='initialview01'>2ajd</scene>, resolution 2.560&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=BPR:(2R)-N-[(2R)-2-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-N-[(5R)-5-(DIHYDROXYBORYL)-1-L-PROLYLPYRROLIDIN-2-YL]-L-PROLINAMIDE'>BPR</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5]
|GENE=
}}
 
'''Porcine dipeptidyl peptidase IV (CD26) in complex with L-Pro-boro-L-Pro (boroPro)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2AJD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=BPR:'>BPR</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJD OCA].  
2AJD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AJD OCA].  


==Reference==
==Reference==
Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV., Engel M, Hoffmann T, Manhart S, Heiser U, Chambre S, Huber R, Demuth HU, Bode W, J Mol Biol. 2006 Jan 27;355(4):768-83. Epub 2005 Nov 22. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16330047 16330047]
Rigidity and flexibility of dipeptidyl peptidase IV: crystal structures of and docking experiments with DPIV., Engel M, Hoffmann T, Manhart S, Heiser U, Chambre S, Huber R, Demuth HU, Bode W, J Mol Biol. 2006 Jan 27;355(4):768-83. Epub 2005 Nov 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16330047 16330047]
[[Category: Dipeptidyl-peptidase IV]]
[[Category: Dipeptidyl-peptidase IV]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: substrate channeling]]
[[Category: substrate channeling]]


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