1sen: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1sen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SEN FirstGlance]. <br>
<table><tr><td colspan='2'>[[1sen]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SEN OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SEN FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene><br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PT:PLATINUM+(II)+ION'>PT</scene></td></tr>
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TLP19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">TLP19 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sen RCSB], [http://www.ebi.ac.uk/pdbsum/1sen PDBsum], [http://www.topsan.org/Proteins/SECSG/1sen TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sen FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sen OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sen RCSB], [http://www.ebi.ac.uk/pdbsum/1sen PDBsum], [http://www.topsan.org/Proteins/SECSG/1sen TOPSAN]</span></td></tr>
<table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/TXD12_HUMAN TXD12_HUMAN]] Possesses significant protein thiol-disulfide oxidase activity.<ref>PMID:12761212</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chen, L.]]
[[Category: Chen, L]]
[[Category: Dailey, H A.]]
[[Category: Dailey, H A]]
[[Category: Dailey, T A.]]
[[Category: Dailey, T A]]
[[Category: Lee, D.]]
[[Category: Lee, D]]
[[Category: Liu, Z J.]]
[[Category: Liu, Z J]]
[[Category: Mayer, M R.]]
[[Category: Mayer, M R]]
[[Category: Richardson, D C.]]
[[Category: Richardson, D C]]
[[Category: Richardson, J S.]]
[[Category: Richardson, J S]]
[[Category: Rose, J P.]]
[[Category: Rose, J P]]
[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
[[Category: Structural genomic]]
[[Category: Shah, A.]]
[[Category: Shah, A]]
[[Category: Tempel, W.]]
[[Category: Tempel, W]]
[[Category: Wang, B C.]]
[[Category: Wang, B C]]
[[Category: Endoplasmic reticulum]]
[[Category: Endoplasmic reticulum]]
[[Category: Protein structure initiative]]
[[Category: PSI, Protein structure initiative]]
[[Category: Psi]]
[[Category: Rp19]]
[[Category: Rp19]]
[[Category: Secsg]]
[[Category: Secsg]]
[[Category: Southeast collaboratory for structural genomic]]
[[Category: Structural genomic]]
[[Category: Unknown function]]
[[Category: Unknown function]]

Revision as of 03:14, 25 December 2014

Endoplasmic reticulum protein Rp19 O95881Endoplasmic reticulum protein Rp19 O95881

Structural highlights

1sen is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:TLP19 (Homo sapiens)
Resources:FirstGlance, OCA, RCSB, PDBsum, TOPSAN

Function

[TXD12_HUMAN] Possesses significant protein thiol-disulfide oxidase activity.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

  1. ↑ Alanen HI, Williamson RA, Howard MJ, Lappi AK, Jantti HP, Rautio SM, Kellokumpu S, Ruddock LW. Functional characterization of ERp18, a new endoplasmic reticulum-located thioredoxin superfamily member. J Biol Chem. 2003 Aug 1;278(31):28912-20. Epub 2003 May 21. PMID:12761212 doi:10.1074/jbc.M304598200

1sen, resolution 1.20Å

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