2aeo: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
[[Image:2aeo.gif|left|200px]]<br /><applet load="2aeo" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2aeo.gif|left|200px]]
caption="2aeo, resolution 1.80&Aring;" />
 
'''Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase'''<br />
{{Structure
|PDB= 2aeo |SIZE=350|CAPTION= <scene name='initialview01'>2aeo</scene>, resolution 1.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=NCP:CIS-DIAMINODICHLOROPLATINUM'>NCP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1]
|GENE=
}}
 
'''Crystal structure of cisplatinated bovine Cu,Zn superoxide dismutase'''
 


==About this Structure==
==About this Structure==
2AEO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=CU:'>CU</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=NCP:'>NCP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEO OCA].  
2AEO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2AEO OCA].  


==Reference==
==Reference==
Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase., Calderone V, Casini A, Mangani S, Messori L, Orioli PL, Angew Chem Int Ed Engl. 2006 Feb 13;45(8):1267-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16416478 16416478]
Structural investigation of cisplatin-protein interactions: selective platination of His19 in a cuprozinc superoxide dismutase., Calderone V, Casini A, Mangani S, Messori L, Orioli PL, Angew Chem Int Ed Engl. 2006 Feb 13;45(8):1267-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16416478 16416478]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Single protein]]
[[Category: Single protein]]
Line 22: Line 31:
[[Category: cisplatin]]
[[Category: cisplatin]]
[[Category: cu]]
[[Category: cu]]
[[Category: metal based drugs]]
[[Category: metal based drug]]
[[Category: platinum]]
[[Category: platinum]]
[[Category: protein]]
[[Category: protein]]
Line 28: Line 37:
[[Category: zn sod]]
[[Category: zn sod]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:26:39 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:48:45 2008''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA