2a8x: Difference between revisions

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[[Image:2a8x.gif|left|200px]]<br /><applet load="2a8x" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2a8x.gif|left|200px]]
caption="2a8x, resolution 2.40&Aring;" />
 
'''Crystal Structure of Lipoamide Dehydrogenase from Mycobacterium tuberculosis'''<br />
{{Structure
|PDB= 2a8x |SIZE=350|CAPTION= <scene name='initialview01'>2a8x</scene>, resolution 2.40&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydrolipoyl_dehydrogenase Dihydrolipoyl dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.4 1.8.1.4]
|GENE= Rv0462, MT0478, lpdC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 Mycobacterium tuberculosis])
}}
 
'''Crystal Structure of Lipoamide Dehydrogenase from Mycobacterium tuberculosis'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2A8X is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=FAD:'>FAD</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydrolipoyl_dehydrogenase Dihydrolipoyl dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.4 1.8.1.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A8X OCA].  
2A8X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A8X OCA].  


==Reference==
==Reference==
Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis., Rajashankar KR, Bryk R, Kniewel R, Buglino JA, Nathan CF, Lima CD, J Biol Chem. 2005 Oct 7;280(40):33977-83. Epub 2005 Aug 10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16093239 16093239]
Crystal structure and functional analysis of lipoamide dehydrogenase from Mycobacterium tuberculosis., Rajashankar KR, Bryk R, Kniewel R, Buglino JA, Nathan CF, Lima CD, J Biol Chem. 2005 Oct 7;280(40):33977-83. Epub 2005 Aug 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16093239 16093239]
[[Category: Dihydrolipoyl dehydrogenase]]
[[Category: Dihydrolipoyl dehydrogenase]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: lipoamide dehydrogenase; pyruvate dehydrogenase; alpha keto acid dehydrogenase; mycobacterium tuberculosis]]
[[Category: lipoamide dehydrogenase; pyruvate dehydrogenase; alpha keto acid dehydrogenase; mycobacterium tuberculosis]]


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