3thp: Difference between revisions
No edit summary |
No edit summary |
||
| Line 9: | Line 9: | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3thp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3thp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3thp RCSB], [http://www.ebi.ac.uk/pdbsum/3thp PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3thp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3thp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3thp RCSB], [http://www.ebi.ac.uk/pdbsum/3thp PDBsum]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/ALKB8_HUMAN ALKB8_HUMAN]] Catalyzes the methylation of 5-carboxymethyl uridine to 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in tRNA. Catalyzes the last step in the formation of 5-methylcarboxymethyl uridine at the wobble position of the anticodon loop in target tRNA. Has a preference for tRNA(Arg) and tRNA(Glu), and does not bind tRNA(Lys). Required for normal survival after DNA damage. May inhibit apoptosis and promote cell survival and angiogenesis.<ref>PMID:19293182</ref> <ref>PMID:20308323</ref> | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||