2a4l: Difference between revisions

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[[Image:2a4l.jpg|left|200px]]<br /><applet load="2a4l" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2a4l.jpg|left|200px]]
caption="2a4l, resolution 2.4&Aring;" />
 
'''Human cyclin-dependent kinase 2 in complex with roscovitine'''<br />
{{Structure
|PDB= 2a4l |SIZE=350|CAPTION= <scene name='initialview01'>2a4l</scene>, resolution 2.4&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=RRC:R-ROSCOVITINE'>RRC</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE=
}}
 
'''Human cyclin-dependent kinase 2 in complex with roscovitine'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2A4L is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=RRC:'>RRC</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4L OCA].  
2A4L is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A4L OCA].  


==Reference==
==Reference==
Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine., De Azevedo WF, Leclerc S, Meijer L, Havlicek L, Strnad M, Kim SH, Eur J Biochem. 1997 Jan 15;243(1-2):518-26. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9030780 9030780]
Inhibition of cyclin-dependent kinases by purine analogues: crystal structure of human cdk2 complexed with roscovitine., De Azevedo WF, Leclerc S, Meijer L, Havlicek L, Strnad M, Kim SH, Eur J Biochem. 1997 Jan 15;243(1-2):518-26. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9030780 9030780]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: transferase]]
[[Category: transferase]]


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