3cwf: Difference between revisions
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cwf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cwf RCSB], [http://www.ebi.ac.uk/pdbsum/3cwf PDBsum], [http://www.topsan.org/Proteins/MCSG/3cwf TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3cwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3cwf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3cwf RCSB], [http://www.ebi.ac.uk/pdbsum/3cwf PDBsum], [http://www.topsan.org/Proteins/MCSG/3cwf TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PHOR_BACSU PHOR_BACSU]] Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. | |||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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[[Category: Bacillus subtilis subsp. subtilis]] | [[Category: Bacillus subtilis subsp. subtilis]] | ||
[[Category: Histidine kinase]] | [[Category: Histidine kinase]] | ||
[[Category: Chang, C | [[Category: Chang, C]] | ||
[[Category: Gu, M | [[Category: Gu, M]] | ||
[[Category: Joachimiak, A | [[Category: Joachimiak, A]] | ||
[[Category: | [[Category: Structural genomic]] | ||
[[Category: Tesar, C | [[Category: Tesar, C]] | ||
[[Category: Alkaline phosphatase synthesis sensor protein phor]] | [[Category: Alkaline phosphatase synthesis sensor protein phor]] | ||
[[Category: Bacillus subtili]] | [[Category: Bacillus subtili]] | ||
| Line 32: | Line 34: | ||
[[Category: Mcsg]] | [[Category: Mcsg]] | ||
[[Category: Membrane]] | [[Category: Membrane]] | ||
[[Category: Pas domain]] | [[Category: Pas domain]] | ||
[[Category: Phosphate transport]] | [[Category: Phosphate transport]] | ||
[[Category: Phosphoprotein]] | [[Category: Phosphoprotein]] | ||
[[Category: Protein structure initiative | [[Category: PSI, Protein structure initiative]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Transmembrane]] | [[Category: Transmembrane]] | ||
[[Category: Transport]] | [[Category: Transport]] | ||
[[Category: Two-component regulatory system]] | [[Category: Two-component regulatory system]] | ||
Revision as of 01:22, 25 December 2014
Crystal structure of PAS domain of two-component sensor histidine kinaseCrystal structure of PAS domain of two-component sensor histidine kinase
Structural highlights
Function[PHOR_BACSU] Member of the two-component regulatory system PhoP/PhoR involved in the alkaline phosphatase genes regulation. PhoR may function as a membrane-associated protein kinase that phosphorylates PhoP in response to environmental signals. Publication Abstract from PubMedWe present the crystal structure of the extracytoplasmic domain of the Bacillus subtilis PhoR sensor histidine kinase, part of a two-component system involved in adaptation to low environmental phosphate concentrations. In addition to the PhoR structure, we predict that the majority of the extracytoplasmic domains of B. subtilis sensor kinases will adopt a fold similar to the ubiquitous PAS domain. Extracytoplasmic PAS-like domains are common in signal transduction proteins.,Chang C, Tesar C, Gu M, Babnigg G, Joachimiak A, Pokkuluri PR, Szurmant H, Schiffer M J Bacteriol. 2010 Feb;192(4):1156-9. Epub 2009 Dec 11. PMID:20008068[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCACategories:
- Bacillus subtilis subsp. subtilis
- Histidine kinase
- Chang, C
- Gu, M
- Joachimiak, A
- Structural genomic
- Tesar, C
- Alkaline phosphatase synthesis sensor protein phor
- Bacillus subtili
- Kinase
- Mcsg
- Membrane
- Pas domain
- Phosphate transport
- Phosphoprotein
- PSI, Protein structure initiative
- Transferase
- Transmembrane
- Transport
- Two-component regulatory system