4np1: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4np1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhopr Rhopr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NP1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NP1 FirstGlance]. <br> | <table><tr><td colspan='2'>[[4np1]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Rhopr Rhopr]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NP1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NP1 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NO:NITRIC+OXIDE'>NO</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4np1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4np1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4np1 RCSB], [http://www.ebi.ac.uk/pdbsum/4np1 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4np1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4np1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4np1 RCSB], [http://www.ebi.ac.uk/pdbsum/4np1 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/NP1_RHOPR NP1_RHOPR]] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Rhopr]] | [[Category: Rhopr]] | ||
[[Category: Andersen, J F | [[Category: Andersen, J F]] | ||
[[Category: Montfort, W R | [[Category: Montfort, W R]] | ||
[[Category: Walker, F A | [[Category: Walker, F A]] | ||
[[Category: Weichsel, A | [[Category: Weichsel, A]] | ||
[[Category: Antihistamine]] | [[Category: Antihistamine]] | ||
[[Category: Heme]] | [[Category: Heme]] | ||
Revision as of 00:51, 25 December 2014
NITROPHORIN 1 COMPLEX WITH NITRIC OXIDENITROPHORIN 1 COMPLEX WITH NITRIC OXIDE
Structural highlights
Function[NP1_RHOPR] Heme-based protein that deliver nitric oxide gas (NO) to the victim while feeding, resulting in vasodilation and inhibition of platelet aggregation. Also bind tightly to histamine, which is released by the host to induce wound healing. Evolutionary Conservation Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf. |
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