1zvx: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1zvx.gif|left|200px]]<br /><applet load="1zvx" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1zvx.gif|left|200px]]
-caption="1zvx, resolution 1.87&Aring;" />
-'''Crystal structure of the complex between MMP-8 and a phosphonate inhibitor (R-enantiomer)'''<br />
+ {{Structure
+|PDB= 1zvx |SIZE=350|CAPTION= <scene name='initialview01'>1zvx</scene>, resolution 1.87&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=FIN:(1R)-1-{[(4'-METHOXY-1,1'-BIPHENYL-4-YL)SULFONYL]AMINO}-2-METHYLPROPYLPHOSPHONIC ACID'>FIN</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34]
+|GENE= MMP8, CLG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Crystal structure of the complex between MMP-8 and a phosphonate inhibitor (R-enantiomer)'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-ZVX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene>, <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=FIN:'>FIN</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Neutrophil_collagenase Neutrophil collagenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.34 3.4.24.34] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZVX OCA].
+ZVX is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZVX OCA].
 ==Reference==
-Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates., Pochetti G, Gavuzzo E, Campestre C, Agamennone M, Tortorella P, Consalvi V, Gallina C, Hiller O, Tschesche H, Tucker PA, Mazza F, J Med Chem. 2006 Feb 9;49(3):923-31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16451058 16451058]
+Structural insight into the stereoselective inhibition of MMP-8 by enantiomeric sulfonamide phosphonates., Pochetti G, Gavuzzo E, Campestre C, Agamennone M, Tortorella P, Consalvi V, Gallina C, Hiller O, Tschesche H, Tucker PA, Mazza F, J Med Chem. 2006 Feb 9;49(3):923-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16451058 16451058]
 [[Category: Homo sapiens]]
 [[Category: Neutrophil collagenase]]
@@ Line 29: / Line 38: @@
 [[Category: ZN]]
 [[Category: hydrolase]]
-[[Category: phosphonic inhibitors]]
+[[Category: phosphonic inhibitor]]
 [[Category: stereoselective inhibition]]
 [[Category: sulfonamide junction]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 16:19:35 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:40:27 2008''