2wnr: Difference between revisions
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<StructureSection load='2wnr' size='340' side='right' caption='[[2wnr]], [[Resolution|resolution]] 2.65Å' scene=''> | <StructureSection load='2wnr' size='340' side='right' caption='[[2wnr]], [[Resolution|resolution]] 2.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wnr]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNR OCA]. <br> | <table><tr><td colspan='2'>[[2wnr]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus Methanothermobacter thermautotrophicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WNR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WNR FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wnr RCSB], [http://www.ebi.ac.uk/pdbsum/2wnr PDBsum]</span></td></tr> | |||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wnr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wnr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wnr RCSB], [http://www.ebi.ac.uk/pdbsum/2wnr PDBsum]</span></td></tr> | </table> | ||
<table> | == Function == | ||
[[http://www.uniprot.org/uniprot/ECX2_METTH ECX2_METTH]] Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site (By similarity). [[http://www.uniprot.org/uniprot/ECX1_METTH ECX1_METTH]] Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails (By similarity). | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring.,Ng CL, Waterman DG, Antson AA, Ortiz-Lombardia M Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):522-8. Epub 2010, Apr 21. PMID:20445227<ref>PMID:20445227</ref> | Structure of the Methanothermobacter thermautotrophicus exosome RNase PH ring.,Ng CL, Waterman DG, Antson AA, Ortiz-Lombardia M Acta Crystallogr D Biol Crystallogr. 2010 May;66(Pt 5):522-8. Epub 2010, Apr 21. PMID:20445227<ref>PMID:20445227</ref> | ||
From | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
== References == | == References == | ||
| Line 30: | Line 31: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Methanothermobacter thermautotrophicus]] | [[Category: Methanothermobacter thermautotrophicus]] | ||
[[Category: Antson, A A | [[Category: Antson, A A]] | ||
[[Category: Ng, C L | [[Category: Ng, C L]] | ||
[[Category: Ortiz-Lombardia, M | [[Category: Ortiz-Lombardia, M]] | ||
[[Category: Waterman, D G | [[Category: Waterman, D G]] | ||
[[Category: 3'-5' exoribonuclease]] | [[Category: 3'-5' exoribonuclease]] | ||
[[Category: Exonuclease]] | [[Category: Exonuclease]] | ||