1xqc: Difference between revisions
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[[Image:1xqc.gif|left|200px]] | [[Image:1xqc.gif|left|200px]] | ||
'''X-ray structure of ERalpha LBD bound to a tetrahydroisoquinoline SERM ligand at 2.05A resolution''' | {{Structure | ||
|PDB= 1xqc |SIZE=350|CAPTION= <scene name='initialview01'>1xqc</scene>, resolution 2.05Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=AEJ:(1S)-1-{4-[(9AR)-OCTAHYDRO-2H-PYRIDO[1,2-A]PYRAZIN-2-YL]PHENYL}-2-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLIN-6-OL'>AEJ</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''X-ray structure of ERalpha LBD bound to a tetrahydroisoquinoline SERM ligand at 2.05A resolution''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1XQC is a [ | 1XQC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XQC OCA]. | ||
==Reference== | ==Reference== | ||
Selective estrogen receptor modulators with conformationally restricted side chains. Synthesis and structure-activity relationship of ERalpha-selective tetrahydroisoquinoline ligands., Renaud J, Bischoff SF, Buhl T, Floersheim P, Fournier B, Geiser M, Halleux C, Kallen J, Keller H, Ramage P, J Med Chem. 2005 Jan 27;48(2):364-79. PMID:[http:// | Selective estrogen receptor modulators with conformationally restricted side chains. Synthesis and structure-activity relationship of ERalpha-selective tetrahydroisoquinoline ligands., Renaud J, Bischoff SF, Buhl T, Floersheim P, Fournier B, Geiser M, Halleux C, Kallen J, Keller H, Ramage P, J Med Chem. 2005 Jan 27;48(2):364-79. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15658851 15658851] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: nuclear hormone receptor]] | [[Category: nuclear hormone receptor]] | ||
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