1xio: Difference between revisions

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Anabaena sensory rhodopsin

OverviewOverview

Microbial sensory rhodopsins are a family of membrane-embedded photoreceptors in prokaryotic and eukaryotic organisms. Structures of archaeal rhodopsins, which function as light-driven ion pumps or photosensors, have been reported. We present the structure of a eubacterial rhodopsin, which differs from those of previously characterized archaeal rhodopsins in its chromophore and cytoplasmic-side portions. Anabaena sensory rhodopsin exhibits light-induced interconversion between stable 13-cis and all-trans states of the retinylidene protein. The ratio of its cis and trans chromophore forms depends on the wavelength of illumination, thus providing a mechanism for a single protein to signal the color of light, for example, to regulate color-sensitive processes such as chromatic adaptation in photosynthesis. Its cytoplasmic half channel, highly hydrophobic in the archaeal rhodopsins, contains numerous hydrophilic residues networked by water molecules, providing a connection from the photoactive site to the cytoplasmic surface believed to interact with the receptor's soluble 14-kilodalton transducer.

About this StructureAbout this Structure

1XIO is a Single protein structure of sequence from Anabaena sp.. Full crystallographic information is available from OCA.

ReferenceReference

Anabaena sensory rhodopsin: a photochromic color sensor at 2.0 A., Vogeley L, Sineshchekov OA, Trivedi VD, Sasaki J, Spudich JL, Luecke H, Science. 2004 Nov 19;306(5700):1390-3. Epub 2004 Sep 30. PMID:15459346

Page seeded by OCA on Thu Mar 20 15:10:26 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1xio.jpg|left|200px]]<br /><applet load="1xio" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1xio.jpg|left|200px]]
-caption="1xio, resolution 2.000&Aring;" />
-'''Anabaena sensory rhodopsin'''<br />
+ {{Structure
+|PDB= 1xio |SIZE=350|CAPTION= <scene name='initialview01'>1xio</scene>, resolution 2.000&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=RET:RETINAL'>RET</scene> and <scene name='pdbligand=PEE:PHOSPHATIDYLETHANOLAMINE'>PEE</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''Anabaena sensory rhodopsin'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-XIO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Anabaena_sp. Anabaena sp.] with <scene name='pdbligand=RET:'>RET</scene> and <scene name='pdbligand=PEE:'>PEE</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XIO OCA].
+XIO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Anabaena_sp. Anabaena sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XIO OCA].
 ==Reference==
-Anabaena sensory rhodopsin: a photochromic color sensor at 2.0 A., Vogeley L, Sineshchekov OA, Trivedi VD, Sasaki J, Spudich JL, Luecke H, Science. 2004 Nov 19;306(5700):1390-3. Epub 2004 Sep 30. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15459346 15459346]
+Anabaena sensory rhodopsin: a photochromic color sensor at 2.0 A., Vogeley L, Sineshchekov OA, Trivedi VD, Sasaki J, Spudich JL, Luecke H, Science. 2004 Nov 19;306(5700):1390-3. Epub 2004 Sep 30. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15459346 15459346]
 [[Category: Anabaena sp.]]
 [[Category: Single protein]]
@@ Line 20: / Line 29: @@
 [[Category: signaling protein]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:55:10 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:10:26 2008''