1xf0: Difference between revisions
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[[Image:1xf0.gif|left|200px]] | [[Image:1xf0.gif|left|200px]] | ||
'''Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP''' | {{Structure | ||
|PDB= 1xf0 |SIZE=350|CAPTION= <scene name='initialview01'>1xf0</scene>, resolution 2.00Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=ASD:4-ANDROSTENE-3-17-DIONE'>ASD</scene> | |||
|ACTIVITY= | |||
|GENE= AKR1C3, DDH1, PGFS, KIAA0119 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1XF0 is a [ | 1XF0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 1XF0 with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb92_1.html Anabolic Steroids]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XF0 OCA]. | ||
==Reference== | ==Reference== | ||
Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues., Qiu W, Zhou M, Labrie F, Lin SX, Mol Endocrinol. 2004 Jul;18(7):1798-807. Epub 2004 Apr 15. PMID:[http:// | Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues., Qiu W, Zhou M, Labrie F, Lin SX, Mol Endocrinol. 2004 Jul;18(7):1798-807. Epub 2004 Apr 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15087468 15087468] | ||
[[Category: Anabolic Steroids]] | [[Category: Anabolic Steroids]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
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[[Category: beta-hairpin]] | [[Category: beta-hairpin]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 15:08:56 2008'' |