1xf0: Difference between revisions

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[[Image:1xf0.gif|left|200px]]<br /><applet load="1xf0" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1xf0.gif|left|200px]]
caption="1xf0, resolution 2.00&Aring;" />
 
'''Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP'''<br />
{{Structure
|PDB= 1xf0 |SIZE=350|CAPTION= <scene name='initialview01'>1xf0</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene> and <scene name='pdbligand=ASD:4-ANDROSTENE-3-17-DIONE'>ASD</scene>
|ACTIVITY=
|GENE= AKR1C3, DDH1, PGFS, KIAA0119 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) complexed with delta4-androstene-3,17-dione and NADP'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1XF0 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=ACT:'>ACT</scene>, <scene name='pdbligand=NAP:'>NAP</scene> and <scene name='pdbligand=ASD:'>ASD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 1XF0 with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb92_1.html Anabolic Steroids]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XF0 OCA].  
1XF0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 1XF0 with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb92_1.html Anabolic Steroids]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XF0 OCA].  


==Reference==
==Reference==
Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues., Qiu W, Zhou M, Labrie F, Lin SX, Mol Endocrinol. 2004 Jul;18(7):1798-807. Epub 2004 Apr 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15087468 15087468]
Crystal structures of the multispecific 17beta-hydroxysteroid dehydrogenase type 5: critical androgen regulation in human peripheral tissues., Qiu W, Zhou M, Labrie F, Lin SX, Mol Endocrinol. 2004 Jul;18(7):1798-807. Epub 2004 Apr 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15087468 15087468]
[[Category: Anabolic Steroids]]
[[Category: Anabolic Steroids]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: beta-hairpin]]
[[Category: beta-hairpin]]


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