1i6z: Difference between revisions
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1i6z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I6Z FirstGlance]. <br> | <table><tr><td colspan='2'>[[1i6z]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1I6Z FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | </td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BAG1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])</td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i6z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1i6z RCSB], [http://www.ebi.ac.uk/pdbsum/1i6z PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i6z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i6z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1i6z RCSB], [http://www.ebi.ac.uk/pdbsum/1i6z PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/BAG1_MOUSE BAG1_MOUSE]] Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Inhibits the pro-apoptotic function of PPP1R15A, and has anti-apoptotic activity. Markedly increases the anti-cell death function of BCL2 induced by various stimuli.<ref>PMID:9873016</ref> | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 32: | Line 34: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Briknarova, K | [[Category: Briknarova, K]] | ||
[[Category: Brive, L | [[Category: Brive, L]] | ||
[[Category: Cabezas, E | [[Category: Cabezas, E]] | ||
[[Category: Ely, K R | [[Category: Ely, K R]] | ||
[[Category: Havert, M L | [[Category: Havert, M L]] | ||
[[Category: Homma, S | [[Category: Homma, S]] | ||
[[Category: Hoyt, D W | [[Category: Hoyt, D W]] | ||
[[Category: Knee, D A | [[Category: Knee, D A]] | ||
[[Category: Llinas, M | [[Category: Llinas, M]] | ||
[[Category: Reed, J C | [[Category: Reed, J C]] | ||
[[Category: Satterthwait, A C | [[Category: Satterthwait, A C]] | ||
[[Category: Stuart, J | [[Category: Stuart, J]] | ||
[[Category: Takayama, S | [[Category: Takayama, S]] | ||
[[Category: Velasco, J | [[Category: Velasco, J]] | ||
[[Category: Chaperone]] | [[Category: Chaperone]] | ||
[[Category: Triple helix bundle]] | [[Category: Triple helix bundle]] | ||