1wzy: Difference between revisions

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[[Image:1wzy.jpg|left|200px]]<br /><applet load="1wzy" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1wzy.jpg|left|200px]]
caption="1wzy, resolution 2.50&Aring;" />
 
'''Crystal structure of human ERK2 complexed with a pyrazolopyridazine derivative'''<br />
{{Structure
|PDB= 1wzy |SIZE=350|CAPTION= <scene name='initialview01'>1wzy</scene>, resolution 2.50&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=F29:1-ALLYL-5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE'>F29</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE=
}}
 
'''Crystal structure of human ERK2 complexed with a pyrazolopyridazine derivative'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1WZY is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=F29:'>F29</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WZY OCA].  
1WZY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WZY OCA].  


==Reference==
==Reference==
Crystal structure of human ERK2 complexed with a pyrazolo[3,4-c]pyridazine derivative., Kinoshita T, Warizaya M, Ohori M, Sato K, Neya M, Fujii T, Bioorg Med Chem Lett. 2006 Jan 1;16(1):55-8. Epub 2005 Oct 18. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16242327 16242327]
Crystal structure of human ERK2 complexed with a pyrazolo[3,4-c]pyridazine derivative., Kinoshita T, Warizaya M, Ohori M, Sato K, Neya M, Fujii T, Bioorg Med Chem Lett. 2006 Jan 1;16(1):55-8. Epub 2005 Oct 18. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16242327 16242327]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: kinase]]
[[Category: kinase]]


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