3lgx: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lgx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lgx RCSB], [http://www.ebi.ac.uk/pdbsum/3lgx PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lgx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lgx OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lgx RCSB], [http://www.ebi.ac.uk/pdbsum/3lgx PDBsum]</span></td></tr>
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== Function ==
[[http://www.uniprot.org/uniprot/DLTA_STRP1 DLTA_STRP1]] Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]

Revision as of 16:56, 24 December 2014

Structure of probable D-alanine-poly(phosphoribitol) ligase subunit-1 from Streptococcus pyogenes with ATPStructure of probable D-alanine-poly(phosphoribitol) ligase subunit-1 from Streptococcus pyogenes with ATP

Structural highlights

3lgx is a 4 chain structure with sequence from Streptococcus pyogenes. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:dltA, M5005_Spy1073, SPy_1312 (Streptococcus pyogenes)
Activity:D-alanine--poly(phosphoribitol) ligase, with EC number 6.1.1.13
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[DLTA_STRP1] Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp (By similarity).

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

3lgx, resolution 2.60Å

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