2cxs: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2cxs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXS FirstGlance]. <br> | <table><tr><td colspan='2'>[[2cxs]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CXS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CXS FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cvp|2cvp]], [[2cxn|2cxn]], [[2cxo|2cxo]], [[2cxp|2cxp]], [[2cxq|2cxq]], [[2cxr|2cxr]], [[2cxt|2cxt]], [[2cxu|2cxu]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2cvp|2cvp]], [[2cxn|2cxn]], [[2cxo|2cxo]], [[2cxp|2cxp]], [[2cxq|2cxq]], [[2cxr|2cxr]], [[2cxt|2cxt]], [[2cxu|2cxu]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucose-6-phosphate_isomerase Glucose-6-phosphate isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.1.9 5.3.1.9] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cxs RCSB], [http://www.ebi.ac.uk/pdbsum/2cxs PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2cxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cxs OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2cxs RCSB], [http://www.ebi.ac.uk/pdbsum/2cxs PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/G6PI_MOUSE G6PI_MOUSE]] Besides it's role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons. | |||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Glucose-6-phosphate isomerase]] | [[Category: Glucose-6-phosphate isomerase]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Funasaka, T | [[Category: Funasaka, T]] | ||
[[Category: Haga, A | [[Category: Haga, A]] | ||
[[Category: Hashimoto, K | [[Category: Hashimoto, K]] | ||
[[Category: Kusakabe, Y | [[Category: Kusakabe, Y]] | ||
[[Category: Naba, N | [[Category: Naba, N]] | ||
[[Category: Nagase, H | [[Category: Nagase, H]] | ||
[[Category: Nakamura, K T | [[Category: Nakamura, K T]] | ||
[[Category: Raz, A | [[Category: Raz, A]] | ||
[[Category: Shiraiwa, K | [[Category: Shiraiwa, K]] | ||
[[Category: Tanaka, N | [[Category: Tanaka, N]] | ||
[[Category: Isomerase]] | [[Category: Isomerase]] | ||