1wk8: Difference between revisions

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[[Image:1wk8.gif|left|200px]]<br /><applet load="1wk8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1wk8.gif|left|200px]]
caption="1wk8, resolution 1.70&Aring;" />
 
'''Isoleucyl-tRNA synthetase editing domain complexed with the pre-transfer editing substrate analogue, Val-AMS'''<br />
{{Structure
|PDB= 1wk8 |SIZE=350|CAPTION= <scene name='initialview01'>1wk8</scene>, resolution 1.70&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=VMS:5'O-[N-(L-VALYL)SULPHAMOYL]ADENOSINE'>VMS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Isoleucine--tRNA_ligase Isoleucine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.5 6.1.1.5]
|GENE= ILES ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=274 Thermus thermophilus])
}}
 
'''Isoleucyl-tRNA synthetase editing domain complexed with the pre-transfer editing substrate analogue, Val-AMS'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1WK8 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus] with <scene name='pdbligand=VMS:'>VMS</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Isoleucine--tRNA_ligase Isoleucine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.5 6.1.1.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WK8 OCA].  
1WK8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WK8 OCA].  


==Reference==
==Reference==
Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase., Fukunaga R, Yokoyama S, J Mol Biol. 2006 Jun 16;359(4):901-12. Epub 2006 Apr 25. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16697013 16697013]
Structural basis for substrate recognition by the editing domain of isoleucyl-tRNA synthetase., Fukunaga R, Yokoyama S, J Mol Biol. 2006 Jun 16;359(4):901-12. Epub 2006 Apr 25. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16697013 16697013]
[[Category: Isoleucine--tRNA ligase]]
[[Category: Isoleucine--tRNA ligase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: fidelity]]
[[Category: fidelity]]
[[Category: isoleucyl-trna synthetase]]
[[Category: isoleucyl-trna synthetase]]
[[Category: national project on protein structural and functional analyses]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nppsfa]]
[[Category: nppsfa]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: rsgi]]
[[Category: structural genomics]]
[[Category: structural genomic]]
[[Category: thermus thermophilus]]
[[Category: thermus thermophilus]]
[[Category: translation]]
[[Category: translation]]


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