2war: Difference between revisions

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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2war FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2war OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2war RCSB], [http://www.ebi.ac.uk/pdbsum/2war PDBsum]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2war FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2war OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2war RCSB], [http://www.ebi.ac.uk/pdbsum/2war PDBsum]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
*[[Lysozyme 3D structures|Lysozyme 3D structures]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chick]]
[[Category: Chick]]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
[[Category: Davies, G J.]]
[[Category: Davies, G J]]
[[Category: Vocadlo, D J.]]
[[Category: Vocadlo, D J]]
[[Category: Withers, S G.]]
[[Category: Withers, S G]]
[[Category: Allergen]]
[[Category: Allergen]]
[[Category: Antimicrobial]]
[[Category: Antimicrobial]]

Revision as of 11:58, 24 December 2014

Hen Egg White Lysozyme E35Q chitopentaose complexHen Egg White Lysozyme E35Q chitopentaose complex

Structural highlights

2war is a 1 chain structure with sequence from Chick. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Activity:Lysozyme, with EC number 3.2.1.17
Resources:FirstGlance, OCA, RCSB, PDBsum

Function

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

References

  1. Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

2war, resolution 1.80Å

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