1uzc: Difference between revisions

Revision as of 15:38, 20 March 2008

Coordinates:

THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11

OverviewOverview

The FF domain is a 60 amino acid residue phosphopeptide-binding module found in a variety of eukaryotic proteins including the transcription elongation factor CA150, the splicing factor Prp40 and p190RHOGAP. We have determined the structure of an FF domain from HYPA/FBP11. The domain is composed of three alpha helices arranged in an orthogonal bundle with a 3(10) helix in the loop between the second and third alpha helices. The structure differs from those of other phosphopeptide-binding domains and represents a novel phosphopeptide-binding fold.

About this StructureAbout this Structure

1UZC is a Single protein structure of sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1H40. Full crystallographic information is available from OCA.

ReferenceReference

The structure of an FF domain from human HYPA/FBP11., Allen M, Friedler A, Schon O, Bycroft M, J Mol Biol. 2002 Oct 25;323(3):411-6. PMID:12381297

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OCA

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-[[Image:1uzc.gif|left|200px]]<br /><applet load="1uzc" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1uzc.gif|left|200px]]
-caption="1uzc" />
-'''THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11'''<br />
+ {{Structure
+|PDB= 1uzc |SIZE=350|CAPTION= <scene name='initialview01'>1uzc</scene>
+|SITE=
+|LIGAND=
+|ACTIVITY=
+|GENE=
+}}
+'''THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-UZC is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1H40. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZC OCA].
+UZC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry 1H40. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZC OCA].
 ==Reference==
-The structure of an FF domain from human HYPA/FBP11., Allen M, Friedler A, Schon O, Bycroft M, J Mol Biol. 2002 Oct 25;323(3):411-6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12381297 12381297]
+The structure of an FF domain from human HYPA/FBP11., Allen M, Friedler A, Schon O, Bycroft M, J Mol Biol. 2002 Oct 25;323(3):411-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12381297 12381297]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
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 [[Category: transcription]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:29:59 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:38:55 2008''