1tw7: Difference between revisions
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[[Image:1tw7.gif|left|200px]] | [[Image:1tw7.gif|left|200px]] | ||
'''Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target''' | {{Structure | ||
|PDB= 1tw7 |SIZE=350|CAPTION= <scene name='initialview01'>1tw7</scene>, resolution 1.3Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=NA:SODIUM ION'>NA</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] | |||
|GENE= HIV-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1]) | |||
}} | |||
'''Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1TW7 is a [ | 1TW7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TW7 OCA]. | ||
==Reference== | ==Reference== | ||
"Wide-open" 1.3 A structure of a multidrug-resistant HIV-1 protease as a drug target., Martin P, Vickrey JF, Proteasa G, Jimenez YL, Wawrzak Z, Winters MA, Merigan TC, Kovari LC, Structure. 2005 Dec;13(12):1887-95. PMID:[http:// | "Wide-open" 1.3 A structure of a multidrug-resistant HIV-1 protease as a drug target., Martin P, Vickrey JF, Proteasa G, Jimenez YL, Wawrzak Z, Winters MA, Merigan TC, Kovari LC, Structure. 2005 Dec;13(12):1887-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16338417 16338417] | ||
[[Category: HIV-1 retropepsin]] | [[Category: HIV-1 retropepsin]] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
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[[Category: Winters, M A.]] | [[Category: Winters, M A.]] | ||
[[Category: NA]] | [[Category: NA]] | ||
[[Category: | [[Category: aid]] | ||
[[Category: aspartyl protease]] | [[Category: aspartyl protease]] | ||
[[Category: hiv protease]] | [[Category: hiv protease]] | ||
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[[Category: polyprotein]] | [[Category: polyprotein]] | ||
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