1tw7: Difference between revisions

No edit summary
No edit summary
Line 1: Line 1:
[[Image:1tw7.gif|left|200px]]<br /><applet load="1tw7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tw7.gif|left|200px]]
caption="1tw7, resolution 1.3&Aring;" />
 
'''Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target'''<br />
{{Structure
|PDB= 1tw7 |SIZE=350|CAPTION= <scene name='initialview01'>1tw7</scene>, resolution 1.3&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NA:SODIUM ION'>NA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16]
|GENE= HIV-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
}}
 
'''Wide Open 1.3A Structure of a Multi-drug Resistant HIV-1 Protease Represents a Novel Drug Target'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
1TW7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=NA:'>NA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/HIV-1_retropepsin HIV-1 retropepsin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.16 3.4.23.16] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TW7 OCA].  
1TW7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TW7 OCA].  


==Reference==
==Reference==
"Wide-open" 1.3 A structure of a multidrug-resistant HIV-1 protease as a drug target., Martin P, Vickrey JF, Proteasa G, Jimenez YL, Wawrzak Z, Winters MA, Merigan TC, Kovari LC, Structure. 2005 Dec;13(12):1887-95. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16338417 16338417]
"Wide-open" 1.3 A structure of a multidrug-resistant HIV-1 protease as a drug target., Martin P, Vickrey JF, Proteasa G, Jimenez YL, Wawrzak Z, Winters MA, Merigan TC, Kovari LC, Structure. 2005 Dec;13(12):1887-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16338417 16338417]
[[Category: HIV-1 retropepsin]]
[[Category: HIV-1 retropepsin]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
Line 23: Line 32:
[[Category: Winters, M A.]]
[[Category: Winters, M A.]]
[[Category: NA]]
[[Category: NA]]
[[Category: aids]]
[[Category: aid]]
[[Category: aspartyl protease]]
[[Category: aspartyl protease]]
[[Category: hiv protease]]
[[Category: hiv protease]]
Line 30: Line 39:
[[Category: polyprotein]]
[[Category: polyprotein]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:18:02 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 14:24:02 2008''

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA