1e5d: Difference between revisions
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==About this Structure== | ==About this Structure== | ||
1E5D is a | 1E5D is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Desulfovibrio_gigas Desulfovibrio gigas] with FMN, FEO and OXY as [http://en.wikipedia.org/wiki/ligands ligands]. Structure known Active Sites: FEA, FEB, FMA and FMB. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1E5D OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: oxygenreductase]] | [[Category: oxygenreductase]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 12:49:59 2007'' | ||
Revision as of 13:44, 5 November 2007
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RUBREDOXIN OXYGEN:OXIDOREDUCTASE (ROO) FROM ANAEROBE DESULFOVIBRIO GIGAS
OverviewOverview
Desulfovibrio gigas is a strict anaerobe that contains a, well-characterized metabolic pathway that enables it to survive transient, contacts with oxygen. The terminal enzyme in this pathway, rubredoxin:oxygen oxidoreductase (ROO) reduces oxygen to water in a direct, and safe way. The 2.5 A resolution crystal structure of ROO shows that, each monomer of this homodimeric enzyme consists of a novel combination of, two domains, a flavodoxin-like domain and a Zn-beta-lactamase-like domain, that contains a di-iron center for dioxygen reduction. This is the first, structure of a member of a superfamily of enzymes widespread in strict and, facultative anaerobes, indicating its broad physiological significance.
About this StructureAbout this Structure
1E5D is a Single protein structure of sequence from Desulfovibrio gigas with FMN, FEO and OXY as ligands. Structure known Active Sites: FEA, FEB, FMA and FMB. Full crystallographic information is available from OCA.
ReferenceReference
Structure of a dioxygen reduction enzyme from Desulfovibrio gigas., Frazao C, Silva G, Gomes CM, Matias P, Coelho R, Sieker L, Macedo S, Liu MY, Oliveira S, Teixeira M, Xavier AV, Rodrigues-Pousada C, Carrondo MA, Le Gall J, Nat Struct Biol. 2000 Nov;7(11):1041-5. PMID:11062560
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Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)
OCA- Pages with broken file links
- Desulfovibrio gigas
- Single protein
- Carrondo, M.A.
- Coelho, R.
- Frazao, C.
- Gall, J.Le.
- Gomes, C.M.
- Liu, M.Y.
- Macedo, S.
- Matias, P.
- Oliveira, S.
- Rodrigues-Pousada, C.
- Sieker, L.
- Silva, G.
- Teixeira, M.
- Xavier, A.V.
- FEO
- FMN
- OXY
- Diiron-centre
- Flavoproteins
- Lactamase-fold
- Oxidoreductase
- Oxygenreductase