1tcv: Difference between revisions

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[[Image:1tcv.gif|left|200px]]<br /><applet load="1tcv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tcv.gif|left|200px]]
caption="1tcv, resolution 1.75&Aring;" />
 
'''Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with Non-detergent Sulfobetaine 195 and acetate'''<br />
{{Structure
|PDB= 1tcv |SIZE=350|CAPTION= <scene name='initialview01'>1tcv</scene>, resolution 1.75&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene> and <scene name='pdbligand=NDS:ETHYL DIMETHYL AMMONIO PROPANE SULFONATE'>NDS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1]
|GENE= SmPNP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6183 Schistosoma mansoni])
}}
 
'''Crystal Structure of the Purine Nucleoside Phosphorylase from Schistosoma mansoni in complex with Non-detergent Sulfobetaine 195 and acetate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TCV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni] with <scene name='pdbligand=ACT:'>ACT</scene> and <scene name='pdbligand=NDS:'>NDS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TCV OCA].  
1TCV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TCV OCA].  


==Reference==
==Reference==
Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis., Pereira HD, Franco GR, Cleasby A, Garratt RC, J Mol Biol. 2005 Oct 28;353(3):584-99. Epub 2005 Sep 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16182308 16182308]
Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis., Pereira HD, Franco GR, Cleasby A, Garratt RC, J Mol Biol. 2005 Oct 28;353(3):584-99. Epub 2005 Sep 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16182308 16182308]
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Schistosoma mansoni]]
[[Category: Schistosoma mansoni]]
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[[Category: purine nucleoside phosphorylase]]
[[Category: purine nucleoside phosphorylase]]


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