1tb6: Difference between revisions

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[[Image:1tb6.jpg|left|200px]]<br /><applet load="1tb6" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1tb6.jpg|left|200px]]
caption="1tb6, resolution 2.50&Aring;" />
 
'''2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex'''<br />
{{Structure
|PDB= 1tb6 |SIZE=350|CAPTION= <scene name='initialview01'>1tb6</scene>, resolution 2.50&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5]
|GENE= F2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), SERPINC1, AT3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''2.5A Crystal Structure of the Antithrombin-Thrombin-Heparin Ternary Complex'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1TB6 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NDG:'>NDG</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Thrombin Thrombin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.5 3.4.21.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TB6 OCA].  
1TB6 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TB6 OCA].  


==Reference==
==Reference==
Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin., Li W, Johnson DJ, Esmon CT, Huntington JA, Nat Struct Mol Biol. 2004 Sep;11(9):857-62. Epub 2004 Aug 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15311269 15311269]
Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin., Li W, Johnson DJ, Esmon CT, Huntington JA, Nat Struct Mol Biol. 2004 Sep;11(9):857-62. Epub 2004 Aug 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15311269 15311269]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: heparin]]
[[Category: heparin]]


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