3ai8: Difference between revisions

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-{{STRUCTURE_3ai8|  PDB=3ai8  |  SCENE=  }}
+==Cathepsin B in complex with the nitroxoline==
-===Cathepsin B in complex with the nitroxoline===
+<StructureSection load='3ai8' size='340' side='right' caption='[[3ai8]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[3ai8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AI8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3AI8 FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/CATB_HUMAN CATB_HUMAN]] Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Has also been implicated in tumor invasion and metastasis.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HNQ:5-NITROQUINOLIN-8-OL'>HNQ</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CTSB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-==About this Structure==
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_B Cathepsin B], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.1 3.4.22.1] </span></td></tr>
-[[3ai8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AI8 OCA].
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ai8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ai8 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3ai8 RCSB], [http://www.ebi.ac.uk/pdbsum/3ai8 PDBsum]</span></td></tr>
+</table>
 ==See Also==
 *[[Cathepsin|Cathepsin]]
+__TOC__
-==Reference==
+</StructureSection>
-<ref group="xtra">PMID:021598397</ref><references group="xtra"/><references/>
 [[Category: Cathepsin B]]
 [[Category: Human]]
-[[Category: Gobec, S.]]
+[[Category: Gobec, S]]
-[[Category: Kos, J.]]
+[[Category: Kos, J]]
-[[Category: Mirkovic, B.]]
+[[Category: Mirkovic, B]]
-[[Category: Renko, M.]]
+[[Category: Renko, M]]
-[[Category: Turk, D.]]
+[[Category: Turk, D]]
 [[Category: 8-hydroxy-5-nitroquinoline]]
 [[Category: Cathepsin b]]