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{{STRUCTURE_4o23|  PDB=4o23  |  SCENE=  }}
==Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from Neisseria meningitidis MC58==
===Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from Neisseria meningitidis MC58===
<StructureSection load='4o23' size='340' side='right' caption='[[4o23]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4o23]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Neimb Neimb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O23 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4O23 FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/DAPE_NEIMB DAPE_NEIMB]] Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity).[HAMAP-Rule:MF_01690]  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3isz|3isz]], [[1vgy|1vgy]]</td></tr>
==About this Structure==
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">dapE, NMB1530 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=122586 NEIMB])</td></tr>
[[4o23]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4O23 OCA].  
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Succinyl-diaminopimelate_desuccinylase Succinyl-diaminopimelate desuccinylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.18 3.5.1.18] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4o23 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4o23 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4o23 RCSB], [http://www.ebi.ac.uk/pdbsum/4o23 PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Neimb]]
[[Category: Succinyl-diaminopimelate desuccinylase]]
[[Category: Succinyl-diaminopimelate desuccinylase]]
[[Category: Anderson, W F.]]
[[Category: Anderson, W F]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Structural genomic]]
[[Category: Holz, R.]]
[[Category: Holz, R]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Nocek, B.]]
[[Category: Nocek, B]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Dape]]
[[Category: Dape]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Structural genomic]]

Revision as of 19:29, 21 December 2014

Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from Neisseria meningitidis MC58Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from Neisseria meningitidis MC58

Structural highlights

4o23 is a 2 chain structure with sequence from Neimb. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:,
Gene:dapE, NMB1530 (NEIMB)
Activity:Succinyl-diaminopimelate desuccinylase, with EC number 3.5.1.18
Resources:FirstGlance, OCA, RCSB, PDBsum

4o23, resolution 2.09Å

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