4mqb: Difference between revisions

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-{{STRUCTURE_4mqb|  PDB=4mqb  |  SCENE=  }}
+==Crystal structure of thymidylate kinase from Staphylococcus aureus in complex with 2-(N-morpholino)ethanesulfonic acid==
-===Crystal structure of thymidylate kinase from Staphylococcus aureus in complex with 2-(N-morpholino)ethanesulfonic acid===
+<StructureSection load='4mqb' size='340' side='right' caption='[[4mqb]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4mqb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MQB FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4eaq|4eaq]], [[4f4i|4f4i]], [[4dwj|4dwj]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tmk, SAV0482 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=158878 Staphylococcus aureus subsp. aureus Mu50])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mqb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mqb OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mqb RCSB], [http://www.ebi.ac.uk/pdbsum/4mqb PDBsum]</span></td></tr>
+</table>
-==Function==
+==See Also==
-[[http://www.uniprot.org/uniprot/KTHY_STAAM KTHY_STAAM]] Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity).
+*[[Thymidylate kinase|Thymidylate kinase]]
+__TOC__
-==About this Structure==
+</StructureSection>
-[[4mqb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_mu50 Staphylococcus aureus subsp. aureus mu50]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MQB OCA].
 [[Category: Staphylococcus aureus subsp. aureus mu50]]
 [[Category: DTMP kinase]]
-[[Category: Anderson, W F.]]
+[[Category: Anderson, W F]]
-[[Category: Babnigg, G.]]
+[[Category: Babnigg, G]]
-[[Category: Filippova, E V.]]
+[[Category: Filippova, E V]]
-[[Category: Jedrzejczak, R.]]
+[[Category: Jedrzejczak, R]]
-[[Category: Joachimiak, A.]]
+[[Category: Joachimiak, A]]
-[[Category: Kiryukhina, O.]]
+[[Category: Kiryukhina, O]]
-[[Category: MCSG, Midwest Center for Structural Genomics.]]
+[[Category: Structural genomic]]
-[[Category: MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors.]]
+[[Category: MTBI, Structures of Mtb Proteins Conferring Susceptibility to Known Mtb Inhibitors]]
-[[Category: Minasov, G.]]
+[[Category: Minasov, G]]
-[[Category: Rubin, E.]]
+[[Category: Rubin, E]]
-[[Category: Sacchettini, J.]]
+[[Category: Sacchettini, J]]
-[[Category: Shuvalova, L.]]
+[[Category: Shuvalova, L]]
 [[Category: Mcsg]]
-[[Category: Midwest center for structural genomic]]
 [[Category: Mtb proteins conferring susceptibility to known mtb inhibitor]]
 [[Category: Mtbi]]
 [[Category: Psi-biology]]
-[[Category: Structural genomic]]
 [[Category: Thymidylate kinase]]
 [[Category: Transferase]]