4hr6: Difference between revisions

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{{STRUCTURE_4hr6|  PDB=4hr6  |  SCENE=  }}
==Crystal structure of snake gourd (Trichosanthes anguina) seed lectin, a three chain homologue of type II RIPs==
===Crystal structure of snake gourd (Trichosanthes anguina) seed lectin, a three chain homologue of type II RIPs===
<StructureSection load='4hr6' size='340' side='right' caption='[[4hr6]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
{{ABSTRACT_PUBMED_11375527}}
== Structural highlights ==
<table><tr><td colspan='2'>[[4hr6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichosanthes_anguina Trichosanthes anguina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HR6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HR6 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMG:ALPHA-METHYL-D-GALACTOSIDE'>AMG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hr6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hr6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hr6 RCSB], [http://www.ebi.ac.uk/pdbsum/4hr6 PDBsum]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
The lectin from the seeds of snake gourd (Trichosanthes anguina) has been crystallized in two forms using the hanging-drop method. Both the forms are hexagonal, with the asymmetric unit containing one subunit consisting of two polypeptide chains linked through disulfide bridges. Intensity data from one of the forms were collected at room temperature as well as at low temperature to 3 A resolution. Molecular-replacement studies indicate that the lectin is homologous to type II ribosome-inactivating proteins. Partial refinement confirms this conclusion.


==About this Structure==
Crystallization and preliminary X-ray studies of snake gourd lectin: homology with type II ribosome-inactivating proteins.,Manoj N, Jeyaprakash AA, Pratap JV, Komath SS, Kenoth R, Swamy MJ, Vijayan M Acta Crystallogr D Biol Crystallogr. 2001 Jun;57(Pt 6):912-4. Epub 2001 May 25. PMID:11375527<ref>PMID:11375527</ref>
[[4hr6]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Trichosanthes_anguina Trichosanthes anguina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HR6 OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
<ref group="xtra">PMID:011375527</ref><references group="xtra"/><references/>
</div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Trichosanthes anguina]]
[[Category: Trichosanthes anguina]]
[[Category: Bobbili, K B.]]
[[Category: Bobbili, K B]]
[[Category: Chandran, T.]]
[[Category: Chandran, T]]
[[Category: Jeyaprakash, A A.]]
[[Category: Jeyaprakash, A A]]
[[Category: Mormann, M.]]
[[Category: Mormann, M]]
[[Category: Pohlentz, G.]]
[[Category: Pohlentz, G]]
[[Category: Sharma, A.]]
[[Category: Sharma, A]]
[[Category: Swamy, M J.]]
[[Category: Swamy, M J]]
[[Category: Vijayan, M.]]
[[Category: Vijayan, M]]
[[Category: Beta-trefoil]]
[[Category: Beta-trefoil]]
[[Category: Carbohydrate]]
[[Category: Carbohydrate]]

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