4hjr: Difference between revisions

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-{{STRUCTURE_4hjr|  PDB=4hjr  |  SCENE=  }}
+==Crystal structure of F2YRS==
-===Crystal structure of F2YRS===
+<StructureSection load='4hjr' size='340' side='right' caption='[[4hjr]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-{{ABSTRACT_PUBMED_23450644}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4hjr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HJR FirstGlance]. <br>
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4hjx|4hjx]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">tyrS, MJ0389 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 Methanocaldococcus jannaschii DSM 2661])</td></tr>
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tyrosine--tRNA_ligase Tyrosine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.1 6.1.1.1] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hjr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hjr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4hjr RCSB], [http://www.ebi.ac.uk/pdbsum/4hjr PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Simple and selective: Tyrosine phosphorylation is a pivotal post-translational modification which regulates the enzymatic activity, protein conformation, and protein-protein interactions. The highly efficient genetic incorporation of 3,5-difluorotyrosine (F2Y) in E. coli and the use of F2Y as a 19 F NMR probe for the tyrosine phosphorylation are reported.
-==Function==
+A Genetically Encoded F NMR Probe for Tyrosine Phosphorylation.,Li F, Shi P, Li J, Yang F, Wang T, Zhang W, Gao F, Ding W, Li D, Li J, Xiong Y, Sun J, Gong W, Tian C, Wang J Angew Chem Int Ed Engl. 2013 Feb 28. doi: 10.1002/anie.201300463. PMID:23450644<ref>PMID:23450644</ref>
-[[http://www.uniprot.org/uniprot/SYY_METJA SYY_METJA]] Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).<ref>PMID:10585437</ref>
-==About this Structure==
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[4hjr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii_dsm_2661 Methanocaldococcus jannaschii dsm 2661]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HJR OCA].
+</div>
-==Reference==
+==See Also==
-<ref group="xtra">PMID:023450644</ref><references group="xtra"/><references/>
+*[[Aminoacyl tRNA Synthetase|Aminoacyl tRNA Synthetase]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Methanocaldococcus jannaschii dsm 2661]]
 [[Category: Tyrosine--tRNA ligase]]
-[[Category: Ding, W.]]
+[[Category: Ding, W]]
-[[Category: Gong, W.]]
+[[Category: Gong, W]]
-[[Category: Li, F.]]
+[[Category: Li, F]]
-[[Category: Li, J.]]
+[[Category: Li, J]]
-[[Category: Shi, P.]]
+[[Category: Shi, P]]
-[[Category: Tian, C.]]
+[[Category: Tian, C]]
-[[Category: Wang, J.]]
+[[Category: Wang, J]]
 [[Category: Aminoacyl-trna synthetase]]
 [[Category: F2y]]
 [[Category: Ligase]]