4eid: Difference between revisions

← Older edit Newer edit →

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-{{STRUCTURE_4eid|  PDB=4eid  |  SCENE=  }}
+==Crystal structure of cytochrome c6 Q57V mutant from Synechococcus sp. PCC 7002==
-===Crystal structure of cytochrome c6 Q57V mutant from Synechococcus sp. PCC 7002===
+<StructureSection load='4eid' size='340' side='right' caption='[[4eid]], [[Resolution|resolution]] 1.13&Aring;' scene=''>
-{{ABSTRACT_PUBMED_19678839}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4eid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechococcus_sp._pcc_7002 Synechococcus sp. pcc 7002]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EID OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EID FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3dr0|3dr0]], [[4eic|4eic]], [[4eie|4eie]], [[4eif|4eif]]</td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">petJ, petJ1, SYNPCC7002_A0167 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=32049 Synechococcus sp. PCC 7002])</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4eid FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eid OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4eid RCSB], [http://www.ebi.ac.uk/pdbsum/4eid PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The structure of the reduced form of cytochrome c(6) from the mesophilic cyanobacterium Synechococcus sp. PCC 7002 has been determined at 1.2 A and refined to an R-factor of 0.107. This protein is unique among all known cytochromes c(6), owing to the presence of an unusual seven-residue insertion, KDGSKSL(44-50), which differs from the insertion found in the recently discovered plant cytochromes c(6A). Furthermore, the present protein is unusual because of its very high content (36%) of the smallest residues (glycine and alanine). The structure reveals that the overall fold of the protein is similar to that of other class I c-type cytochromes, despite the presence of the specific insertion. The insertion is located within the most variable region of the cytochrome c(6) sequence, i.e. between helices II and III. The first six residues [KDGSKS(44-49)] form a loop, whereas the last residue, Leu50, extends the N-terminal beginning of helix III. Several specific noncovalent interactions are found inside the insertion, as well as between the insertion and the rest of the protein. The crystal structure contains three copies of the cytochrome c(6) molecule per asymmetric unit, and is characterized by an unusually high packing density, with solvent occupying barely 17.58% of the crystal volume.
-==Function==
+Atomic-resolution structure of reduced cyanobacterial cytochrome c6 with an unusual sequence insertion.,Bialek W, Krzywda S, Jaskolski M, Szczepaniak A FEBS J. 2009 Aug;276(16):4426-36. PMID:19678839<ref>PMID:19678839</ref>
-[[http://www.uniprot.org/uniprot/CYC6_SYNP2 CYC6_SYNP2]] Functions as an electron carrier between membrane-bound cytochrome b6-f and photosystem I in oxygenic photosynthesis (By similarity).
-==About this Structure==
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[4eid]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Synechococcus_sp._pcc_7002 Synechococcus sp. pcc 7002]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EID OCA].
+</div>
-==Reference==
+==See Also==
-<ref group="xtra">PMID:019678839</ref><ref group="xtra">PMID:018439023</ref><references group="xtra"/><references/>
+*[[Cytochrome c|Cytochrome c]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Synechococcus sp. pcc 7002]]
-[[Category: Bialek, W.]]
+[[Category: Bialek, W]]
-[[Category: Jaskolski, M.]]
+[[Category: Jaskolski, M]]
-[[Category: Krzywda, S.]]
+[[Category: Krzywda, S]]
-[[Category: Szczepaniak, A.]]
+[[Category: Szczepaniak, A]]
-[[Category: Zatwarnicki, P.]]
+[[Category: Zatwarnicki, P]]
 [[Category: Cytochrome c6]]
 [[Category: Electron transport]]