4arr: Difference between revisions

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-{{STRUCTURE_4arr|  PDB=4arr  |  SCENE=  }}
+==Crystal structure of the N-terminal domain of Drosophila Toll receptor with the magic triangle I3C==
-===Crystal structure of the N-terminal domain of Drosophila Toll receptor with the magic triangle I3C===
+<StructureSection load='4arr' size='340' side='right' caption='[[4arr]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-{{ABSTRACT_PUBMED_23596340}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4arr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ARR FirstGlance]. <br>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I3C:5-AMINO-2,4,6-TRIIODOBENZENE-1,3-DICARBOXYLIC+ACID'>I3C</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4arn|4arn]]</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4arr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4arr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4arr RCSB], [http://www.ebi.ac.uk/pdbsum/4arr PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+Generating high-quality crystals remains a bottleneck in biological and materials sciences. Here a counter-diffusion method was used to improve the X-ray diffraction quality of the N-terminal domain of Drosophila melanogaster Toll receptor crystals. It was observed that crystallization occurred with a peculiar pattern along the capillary resembling Liesegang bands; this phenomenon is described at both macroscopic and atomic levels. It was found that bands appeared for native protein as well as for co-crystals of magic triangle (I3C)-bound protein even though they crystallize in different space groups. Crystallization occurred with a linear recurrence independent of the precipitant concentration and a protein-specific spacing coefficient. Bandwidth varied along the capillary, oscillating between large precipitation areas and single crystals. The reported data suggest that repetitive patterns can be generated with biological macromolecules in the presence of sodium malonate as a crystallization agent. A comparison with typical Liesegang patterns and the possible mechanism underlying this phenomenon are discussed.
-==About this Structure==
+Liesegang-like patterns of Toll crystals grown in gel.,Gangloff M, Moreno A, Gay NJ J Appl Crystallogr. 2013 Apr 1;46(Pt 2):337-345. Epub 2013 Feb 14. PMID:23596340<ref>PMID:23596340</ref>
-[[4arr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster,_eptatretus_burgeri Drosophila melanogaster, eptatretus burgeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ARR OCA].
-[[Category: Drosophila melanogaster, eptatretus burgeri]]
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-[[Category: Gangloff, M.]]
+</div>
-[[Category: Gay, N J.]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Drome]]
+[[Category: Gangloff, M]]
+[[Category: Gay, N J]]
 [[Category: Cytokine receptor]]
 [[Category: Embryonic development]]