1rnd: Difference between revisions

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Revision as of 14:53, 20 March 2008

File:1rnd.gif

, resolution 1.5Å

Ligands:

and

Activity:

Pancreatic ribonuclease, with EC number 3.1.27.5

Coordinates:

save as pdb, mmCIF, xml

NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE

OverviewOverview

Dinucleotides containing guanine, when soaked into crystals of bovine pancreatic ribonuclease, have been found to bind in an unexpected manner, quite unlike interpretations of earlier X-ray diffraction studies. This finding has prompted a reexamination of three mononucleotide-RNase complexes from this laboratory resulting in a re-interpretation of the complex that involved a guanine mononucleotide.

About this StructureAbout this Structure

1RND is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

ReferenceReference

Newly observed binding mode in pancreatic ribonuclease., Aguilar CF, Thomas PJ, Mills A, Moss DS, Palmer RA, J Mol Biol. 1992 Mar 5;224(1):265-7. PMID:1548704

Page seeded by OCA on Thu Mar 20 13:53:50 2008

Proteopedia Page Contributors and Editors (what is this?)Proteopedia Page Contributors and Editors (what is this?)

OCA

@@ Line 1: / Line 1: @@
-[[Image:1rnd.gif|left|200px]]<br /><applet load="1rnd" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1rnd.gif|left|200px]]
-caption="1rnd, resolution 1.5&Aring;" />
-'''NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE'''<br />
+ {{Structure
+|PDB= 1rnd |SIZE=350|CAPTION= <scene name='initialview01'>1rnd</scene>, resolution 1.5&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=DGP:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DGP</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5]
+|GENE=
+}}
+'''NEWLY OBSERVED BINDING MODE IN PANCREATIC RIBONUCLEASE'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-RND is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=DGP:'>DGP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RND OCA].
+RND is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RND OCA].
 ==Reference==
-Newly observed binding mode in pancreatic ribonuclease., Aguilar CF, Thomas PJ, Mills A, Moss DS, Palmer RA, J Mol Biol. 1992 Mar 5;224(1):265-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1548704 1548704]
+Newly observed binding mode in pancreatic ribonuclease., Aguilar CF, Thomas PJ, Mills A, Moss DS, Palmer RA, J Mol Biol. 1992 Mar 5;224(1):265-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/1548704 1548704]
 [[Category: Bos taurus]]
 [[Category: Pancreatic ribonuclease]]
@@ Line 23: / Line 32: @@
 [[Category: hydrolase(endoribonuclease)]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:52:38 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:53:50 2008''