1re8: Difference between revisions
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[[Image:1re8.gif|left|200px]] | [[Image:1re8.gif|left|200px]] | ||
'''Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 2''' | {{Structure | ||
|PDB= 1re8 |SIZE=350|CAPTION= <scene name='initialview01'>1re8</scene>, resolution 2.1Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=BD2:3-[(4-HYDROXYBENZOYL)AMINO]AZEPAN-4-YL+4-(2-HYDROXYBENZOYL)BENZOATE'>BD2</scene> and <scene name='pdbligand=OCT:N-OCTANE'>OCT</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] | |||
|GENE= PRKACA, PKACA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus]) | |||
}} | |||
'''Crystal structure of cAMP-dependent protein kinase complexed with balanol analog 2''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1RE8 is a [ | 1RE8 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RE8 OCA]. | ||
==Reference== | ==Reference== | ||
Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit., Akamine P, Madhusudan, Brunton LL, Ou HD, Canaves JM, Xuong NH, Taylor SS, Biochemistry. 2004 Jan 13;43(1):85-96. PMID:[http:// | Balanol analogues probe specificity determinants and the conformational malleability of the cyclic 3',5'-adenosine monophosphate-dependent protein kinase catalytic subunit., Akamine P, Madhusudan, Brunton LL, Ou HD, Canaves JM, Xuong NH, Taylor SS, Biochemistry. 2004 Jan 13;43(1):85-96. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14705934 14705934] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
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[[Category: natural product inhibitor]] | [[Category: natural product inhibitor]] | ||
[[Category: protein kinase]] | [[Category: protein kinase]] | ||
[[Category: specificity | [[Category: specificity determinant]] | ||
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