3w0t: Difference between revisions

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-{{STRUCTURE_3w0t|  PDB=3w0t  |  SCENE=  }}
+==Human Glyoxalase I with an N-hydroxypyridone derivative inhibitor==
-===Human Glyoxalase I with an N-hydroxypyridone derivative inhibitor===
+<StructureSection load='3w0t' size='340' side='right' caption='[[3w0t]], [[Resolution|resolution]] 1.35&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[3w0t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W0T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3W0T FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/LGUL_HUMAN LGUL_HUMAN]] Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B.<ref>PMID:19199007</ref>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=HPU:N-[3-(1-HYDROXY-6-OXO-4-PHENYL-1,6-DIHYDROPYRIDIN-2-YL)PHENYL]METHANESULFONAMIDE'>HPU</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vw9|3vw9]], [[3w0u|3w0u]]</td></tr>
-==About this Structure==
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">GLO1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-[[3w0t]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W0T OCA].
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lactoylglutathione_lyase Lactoylglutathione lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.5 4.4.1.5] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3w0t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w0t OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3w0t RCSB], [http://www.ebi.ac.uk/pdbsum/3w0t PDBsum]</span></td></tr>
-==Reference==
+</table>
-<references group="xtra"/><references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
 [[Category: Lactoylglutathione lyase]]
-[[Category: Fukami, T A.]]
+[[Category: Fukami, T A]]
-[[Category: Irie, M.]]
+[[Category: Irie, M]]
-[[Category: Matsuura, T.]]
+[[Category: Matsuura, T]]
 [[Category: Glyoxalase]]
 [[Category: Lyase-lyase inhibitor complex]]