1r6u: Difference between revisions

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[[Image:1r6u.jpg|left|200px]]<br /><applet load="1r6u" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1r6u.jpg|left|200px]]
caption="1r6u, resolution 2.0&Aring;" />
 
'''Crystal structure of an active fragment of human tryptophanyl-tRNA synthetase with cytokine activity'''<br />
{{Structure
|PDB= 1r6u |SIZE=350|CAPTION= <scene name='initialview01'>1r6u</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=TYM:TRYPTOPHANYL-5'AMP'>TYM</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Tryptophan--tRNA_ligase Tryptophan--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.2 6.1.1.2]
|GENE= WARS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of an active fragment of human tryptophanyl-tRNA synthetase with cytokine activity'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1R6U is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=TYM:'>TYM</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Tryptophan--tRNA_ligase Tryptophan--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.2 6.1.1.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6U OCA].  
1R6U is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R6U OCA].  


==Reference==
==Reference==
Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase., Yang XL, Guo M, Kapoor M, Ewalt KL, Otero FJ, Skene RJ, McRee DE, Schimmel P, Structure. 2007 Jul;15(7):793-805. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17637340 17637340]
Functional and crystal structure analysis of active site adaptations of a potent anti-angiogenic human tRNA synthetase., Yang XL, Guo M, Kapoor M, Ewalt KL, Otero FJ, Skene RJ, McRee DE, Schimmel P, Structure. 2007 Jul;15(7):793-805. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17637340 17637340]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: rossmann fold catalytic domain]]
[[Category: rossmann fold catalytic domain]]


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