1r0a: Difference between revisions

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[[Image:1r0a.gif|left|200px]]<br /><applet load="1r0a" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1r0a.gif|left|200px]]
caption="1r0a, resolution 2.80&Aring;" />
 
'''Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms'''<br />
{{Structure
|PDB= 1r0a |SIZE=350|CAPTION= <scene name='initialview01'>1r0a</scene>, resolution 2.80&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=GLC:GLUCOSE'>GLC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
}}
 
'''Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1R0A is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=GLC:'>GLC</scene>, <scene name='pdbligand=MG:'>MG</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R0A OCA].  
1R0A is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R0A OCA].  


==Reference==
==Reference==
Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA., Peletskaya EN, Kogon AA, Tuske S, Arnold E, Hughes SH, J Virol. 2004 Apr;78(7):3387-97. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15016861 15016861]
Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA., Peletskaya EN, Kogon AA, Tuske S, Arnold E, Hughes SH, J Virol. 2004 Apr;78(7):3387-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15016861 15016861]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: transferase]]
[[Category: transferase]]


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