1r0a: Difference between revisions
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[[Image:1r0a.gif|left|200px]] | [[Image:1r0a.gif|left|200px]] | ||
'''Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms''' | {{Structure | ||
|PDB= 1r0a |SIZE=350|CAPTION= <scene name='initialview01'>1r0a</scene>, resolution 2.80Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=GLC:GLUCOSE'>GLC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] | |||
|GENE= POL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1]) | |||
}} | |||
'''Crystal structure of HIV-1 reverse transcriptase covalently tethered to DNA template-primer solved to 2.8 angstroms''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1R0A is a [ | 1R0A is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1R0A OCA]. | ||
==Reference== | ==Reference== | ||
Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA., Peletskaya EN, Kogon AA, Tuske S, Arnold E, Hughes SH, J Virol. 2004 Apr;78(7):3387-97. PMID:[http:// | Nonnucleoside inhibitor binding affects the interactions of the fingers subdomain of human immunodeficiency virus type 1 reverse transcriptase with DNA., Peletskaya EN, Kogon AA, Tuske S, Arnold E, Hughes SH, J Virol. 2004 Apr;78(7):3387-97. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15016861 15016861] | ||
[[Category: Human immunodeficiency virus 1]] | [[Category: Human immunodeficiency virus 1]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
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[[Category: transferase]] | [[Category: transferase]] | ||
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