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==HCV NS3-4a protease domain with ketoamide inhibitor narlaprevir== | |||
<StructureSection load='3lon' size='340' side='right' caption='[[3lon]], [[Resolution|resolution]] 2.20Å' scene=''> | |||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[3lon]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LON OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3LON FirstGlance]. <br> | ||
[[3lon]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_subtype_1a Hepatitis c virus subtype 1a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LON OCA]. | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=NNA:(1R,2S,5S)-3-[N-({1-[(TERT-BUTYLSULFONYL)METHYL]CYCLOHEXYL}CARBAMOYL)-3-METHYL-L-VALYL]-N-{(1S)-1-[(1R)-2-(CYCLOPROPYLAMINO)-1-HYDROXY-2-OXOETHYL]PENTYL}-6,6-DIMETHYL-3-AZABICYCLO[3.1.0]HEXANE-2-CARBOXAMIDE'>NNA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NS3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=31646 Hepatitis C virus subtype 1a])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3lon FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lon OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3lon RCSB], [http://www.ebi.ac.uk/pdbsum/3lon PDBsum]</span></td></tr> | |||
</table> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Hepatitis c virus subtype 1a]] | [[Category: Hepatitis c virus subtype 1a]] | ||
[[Category: Prongay, A J | [[Category: Prongay, A J]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Capsid protein]] | [[Category: Capsid protein]] | ||
Revision as of 19:51, 18 December 2014
HCV NS3-4a protease domain with ketoamide inhibitor narlaprevirHCV NS3-4a protease domain with ketoamide inhibitor narlaprevir
Structural highlights
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