3n2l: Difference between revisions

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{{STRUCTURE_3n2l|  PDB=3n2l  |  SCENE=  }}
==2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961==
===2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961===
<StructureSection load='3n2l' size='340' side='right' caption='[[3n2l]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[3n2l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3N2L FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/PYRE_VIBCH PYRE_VIBCH]] Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity).  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrE, VC_0211 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=666 Vibrio cholerae])</td></tr>
==About this Structure==
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotate_phosphoribosyltransferase Orotate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.10 2.4.2.10] </span></td></tr>
[[3n2l]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N2L OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3n2l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n2l OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3n2l RCSB], [http://www.ebi.ac.uk/pdbsum/3n2l PDBsum]</span></td></tr>
</table>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n2/3n2l_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
*[[Phosphoribosyltransferase|Phosphoribosyltransferase]]
__TOC__
</StructureSection>
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Vibrio cholerae]]
[[Category: Vibrio cholerae]]
[[Category: Anderson, W F.]]
[[Category: Anderson, W F]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Structural genomic]]
[[Category: Dubrovska, I.]]
[[Category: Dubrovska, I]]
[[Category: Halavaty, A S.]]
[[Category: Halavaty, A S]]
[[Category: Kwon, K.]]
[[Category: Kwon, K]]
[[Category: Minasov, G.]]
[[Category: Minasov, G]]
[[Category: Shuvalova, L.]]
[[Category: Shuvalova, L]]
[[Category: Winsor, J.]]
[[Category: Winsor, J]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Csgid]]
[[Category: Glycosyltransferase]]
[[Category: Glycosyltransferase]]
[[Category: Infectious disease]]
[[Category: Infectious disease]]
[[Category: Magnesium]]
[[Category: Magnesium]]
[[Category: Orotate phosphoribosyltransferase]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine biosynthesis]]
[[Category: Pyrimidine ribonucleotide biosynthesis]]
[[Category: Pyrimidine ribonucleotide biosynthesis]]
[[Category: Transferase]]
[[Category: Transferase]]

Revision as of 19:06, 18 December 2014

2.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N169612.1 Angstrom resolution crystal structure of an Orotate Phosphoribosyltransferase (pyrE) from Vibrio cholerae O1 biovar eltor str. N16961

Structural highlights

3n2l is a 8 chain structure with sequence from Vibrio cholerae. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Ligands:
Gene:pyrE, VC_0211 (Vibrio cholerae)
Activity:Orotate phosphoribosyltransferase, with EC number 2.4.2.10
Resources:FirstGlance, OCA, RCSB, PDBsum

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

3n2l, resolution 2.10Å

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