1owk: Difference between revisions

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OCA

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-[[Image:1owk.gif|left|200px]]<br /><applet load="1owk" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1owk.gif|left|200px]]
-caption="1owk, resolution 2.80&Aring;" />
-'''Substituted 2-Naphthamidine Inhibitors of Urokinase'''<br />
+ {{Structure
+|PDB= 1owk |SIZE=350|CAPTION= <scene name='initialview01'>1owk</scene>, resolution 2.80&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=303:6-[(Z)-AMINO(IMINO)METHYL]-N-(1-ISOPROPYL-1,2,3,4-TETRAHYDROISOQUINOLIN-7-YL)-2-NAPHTHAMIDE'>303</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/U-plasminogen_activator U-plasminogen activator], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.73 3.4.21.73]
+|GENE= PLAU ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''Substituted 2-Naphthamidine Inhibitors of Urokinase'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-OWK is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=303:'>303</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/U-plasminogen_activator U-plasminogen activator], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.73 3.4.21.73] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWK OCA].
+OWK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OWK OCA].
 ==Reference==
-Identification of novel binding interactions in the development of potent, selective 2-naphthamidine inhibitors of urokinase. Synthesis, structural analysis, and SAR of N-phenyl amide 6-substitution., Wendt MD, Rockway TW, Geyer A, McClellan W, Weitzberg M, Zhao X, Mantei R, Nienaber VL, Stewart K, Klinghofer V, Giranda VL, J Med Chem. 2004 Jan 15;47(2):303-24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14711304 14711304]
+Identification of novel binding interactions in the development of potent, selective 2-naphthamidine inhibitors of urokinase. Synthesis, structural analysis, and SAR of N-phenyl amide 6-substitution., Wendt MD, Rockway TW, Geyer A, McClellan W, Weitzberg M, Zhao X, Mantei R, Nienaber VL, Stewart K, Klinghofer V, Giranda VL, J Med Chem. 2004 Jan 15;47(2):303-24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14711304 14711304]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
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 [[Category: serine protease]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:22:23 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:16:38 2008''