1ovd: Difference between revisions

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[[Image:1ovd.jpg|left|200px]]<br /><applet load="1ovd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:1ovd.jpg|left|200px]]
caption="1ovd, resolution 2.25&Aring;" />
 
'''THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE'''<br />
{{Structure
|PDB= 1ovd |SIZE=350|CAPTION= <scene name='initialview01'>1ovd</scene>, resolution 2.25&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=ORO:OROTIC+ACID'>ORO</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydroorotate_oxidase Dihydroorotate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.1 1.3.3.1]
|GENE= PYRDA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1358 Lactococcus lactis])
}}
 
'''THE K136E MUTANT OF LACTOCOCCUS LACTIS DIHYDROOROTATE DEHYDROGENASE A IN COMPLEX WITH OROTATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
1OVD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=FMN:'>FMN</scene>, <scene name='pdbligand=ORO:'>ORO</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydroorotate_oxidase Dihydroorotate oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.3.3.1 1.3.3.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OVD OCA].  
1OVD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Lactococcus_lactis Lactococcus lactis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OVD OCA].  


==Reference==
==Reference==
Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function., Norager S, Arent S, Bjornberg O, Ottosen M, Lo Leggio L, Jensen KF, Larsen S, J Biol Chem. 2003 Aug 1;278(31):28812-22. Epub 2003 May 5. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=12732650 12732650]
Lactococcus lactis dihydroorotate dehydrogenase A mutants reveal important facets of the enzymatic function., Norager S, Arent S, Bjornberg O, Ottosen M, Lo Leggio L, Jensen KF, Larsen S, J Biol Chem. 2003 Aug 1;278(31):28812-22. Epub 2003 May 5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12732650 12732650]
[[Category: Dihydroorotate oxidase]]
[[Category: Dihydroorotate oxidase]]
[[Category: Lactococcus lactis]]
[[Category: Lactococcus lactis]]
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[[Category: orotate complex]]
[[Category: orotate complex]]


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