1oo5: Difference between revisions
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[[Image:1oo5.jpg|left|200px]] | [[Image:1oo5.jpg|left|200px]] | ||
'''Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of the Enzyme Active Form and Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs''' | {{Structure | ||
|PDB= 1oo5 |SIZE=350|CAPTION= <scene name='initialview01'>1oo5</scene>, resolution 2.50Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=FMN:FLAVIN MONONUCLEOTIDE'>FMN</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/6,7-dihydropteridine_reductase 6,7-dihydropteridine reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.34 1.5.1.34] | |||
|GENE= | |||
}} | |||
'''Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of the Enzyme Active Form and Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1OO5 is a [ | 1OO5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OO5 OCA]. | ||
==Reference== | ==Reference== | ||
Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form., Johansson E, Parkinson GN, Denny WA, Neidle S, J Med Chem. 2003 Sep 11;46(19):4009-20. PMID:[http:// | Studies on the nitroreductase prodrug-activating system. Crystal structures of complexes with the inhibitor dicoumarol and dinitrobenzamide prodrugs and of the enzyme active form., Johansson E, Parkinson GN, Denny WA, Neidle S, J Med Chem. 2003 Sep 11;46(19):4009-20. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12954054 12954054] | ||
[[Category: 6,7-dihydropteridine reductase]] | [[Category: 6,7-dihydropteridine reductase]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
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[[Category: nitroreductase]] | [[Category: nitroreductase]] | ||
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