1ol2: Difference between revisions
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[[Image:1ol2.gif|left|200px]] | [[Image:1ol2.gif|left|200px]] | ||
'''CYCLIN A BINDING GROOVE INHIBITOR H-ARG-ARG-LEU-ASN-(P-F-PHE)-NH2''' | {{Structure | ||
|PDB= 1ol2 |SIZE=350|CAPTION= <scene name='initialview01'>1ol2</scene>, resolution 2.6Å | |||
|SITE= <scene name='pdbsite=CBB:Cyclin+Binding+Groove+Chain+D'>CBB</scene> | |||
|LIGAND= <scene name='pdbligand=NH2:AMINO GROUP'>NH2</scene> | |||
|ACTIVITY= [http://en.wikipedia.org/wiki/Transferred_entry:_2.7.11.1 Transferred entry: 2.7.11.1], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.37 2.7.1.37] | |||
|GENE= | |||
}} | |||
'''CYCLIN A BINDING GROOVE INHIBITOR H-ARG-ARG-LEU-ASN-(P-F-PHE)-NH2''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
1OL2 is a [ | 1OL2 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OL2 OCA]. | ||
==Reference== | ==Reference== | ||
Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange., Kontopidis G, Andrews MJ, McInnes C, Cowan A, Powers H, Innes L, Plater A, Griffiths G, Paterson D, Zheleva DI, Lane DP, Green S, Walkinshaw MD, Fischer PM, Structure. 2003 Dec;11(12):1537-46. PMID:[http:// | Insights into cyclin groove recognition: complex crystal structures and inhibitor design through ligand exchange., Kontopidis G, Andrews MJ, McInnes C, Cowan A, Powers H, Innes L, Plater A, Griffiths G, Paterson D, Zheleva DI, Lane DP, Green S, Walkinshaw MD, Fischer PM, Structure. 2003 Dec;11(12):1537-46. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14656438 14656438] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Protein complex]] | [[Category: Protein complex]] | ||
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[[Category: Zheleva, D.]] | [[Category: Zheleva, D.]] | ||
[[Category: NH2]] | [[Category: NH2]] | ||
[[Category: cyclin | [[Category: cyclin some]] | ||
[[Category: drug design]] | [[Category: drug design]] | ||
[[Category: inhibitor]] | [[Category: inhibitor]] | ||
[[Category: kinase]] | [[Category: kinase]] | ||
[[Category: ligand exchange]] | [[Category: ligand exchange]] | ||
[[Category: | [[Category: peptidomimetic]] | ||
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