1vw4: Difference between revisions

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==Structure of the yeast mitochondrial large ribosomal subunit==
#REDIRECT [[3j6b]] This PDB entry is obsolete and replaced by 3j6b
<StructureSection load='1vw4' size='340' side='right' caption='[[1vw4]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1vw4]] is a 36 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VW4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VW4 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3j6b|3j6b]], [[1vw3|1vw3]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vw4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vw4 RCSB], [http://www.ebi.ac.uk/pdbsum/1vw4 PDBsum]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Mitochondria have specialized ribosomes that have diverged from their bacterial and cytoplasmic counterparts. We have solved the structure of the yeast mitoribosomal large subunit using single-particle cryo-electron microscopy. The resolution of 3.2 angstroms enabled a nearly complete atomic model to be built de novo and refined, including 39 proteins, 13 of which are unique to mitochondria, as well as expansion segments of mitoribosomal RNA. The structure reveals a new exit tunnel path and architecture, unique elements of the E site, and a putative membrane docking site.
 
Structure of the yeast mitochondrial large ribosomal subunit.,Amunts A, Brown A, Bai XC, Llacer JL, Hussain T, Emsley P, Long F, Murshudov G, Scheres SH, Ramakrishnan V Science. 2014 Mar 28;343(6178):1485-9. doi: 10.1126/science.1249410. PMID:24675956<ref>PMID:24675956</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Saccharomyces cerevisiae]]
[[Category: Amunts, A]]
[[Category: Bai, X C]]
[[Category: Brown, A]]
[[Category: Emsley, P]]
[[Category: Hussain, T]]
[[Category: Llacer, J L]]
[[Category: Long, F]]
[[Category: Murshudov, G]]
[[Category: Ramakrishnan, V]]
[[Category: Scheres, S H.W]]
[[Category: Large subunit]]
[[Category: Mitochondrial ribosome]]
[[Category: Protein-rna complex]]
[[Category: Ribosome]]

Latest revision as of 18:05, 10 December 2014

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