1o4e: Difference between revisions

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OCA

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-[[Image:1o4e.jpg|left|200px]]<br /><applet load="1o4e" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:1o4e.jpg|left|200px]]
-caption="1o4e, resolution 2.00&Aring;" />
-'''CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78299.'''<br />
+ {{Structure
+|PDB= 1o4e |SIZE=350|CAPTION= <scene name='initialview01'>1o4e</scene>, resolution 2.00&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=299:2,6-DIFORMYL-4-METHYLPHENYL DIHYDROGEN PHOSPHATE'>299</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2]
+|GENE= SRC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
+}}
+'''CRYSTAL STRUCTURE OF SH2 IN COMPLEX WITH RU78299.'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-O4E is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=299:'>299</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4E OCA].
+O4E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1O4E OCA].
 ==Reference==
-Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors., Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E, J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=14613321 14613321]
+Requirements for specific binding of low affinity inhibitor fragments to the SH2 domain of (pp60)Src are identical to those for high affinity binding of full length inhibitors., Lange G, Lesuisse D, Deprez P, Schoot B, Loenze P, Benard D, Marquette JP, Broto P, Sarubbi E, Mandine E, J Med Chem. 2003 Nov 20;46(24):5184-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14613321 14613321]
 [[Category: Homo sapiens]]
 [[Category: Single protein]]
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 [[Category: sh2 domain fragment approach]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 14:13:20 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:05:39 2008''