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[[ | ==Crystal Structure of d(CCGGGACCGG)4 as a four-way junction at 1.6 angstrom resolution== | ||
<StructureSection load='4ez2' size='340' side='right' caption='[[4ez2]], [[Resolution|resolution]] 1.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4ez2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EZ2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4EZ2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[467d|467d]]</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4ez2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ez2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4ez2 RCSB], [http://www.ebi.ac.uk/pdbsum/4ez2 PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
The crystal structure of the decamer sequence d(CCGGGACCGG)(4) has previously been reported at 2.16 A resolution as a four-way junction. Here, the structure of this sequence is reported at the significantly higher resolution of 1.6 A, which is the highest resolution reported for a four-way junction. This allowed the unambiguous identification of an extensive hydration network with distinct patterns and solvent-mediated interactions that shed new light on the role of water in the formation and stabilization of junction structures. | |||
Structure of d(CCGGGACCGG)(4) as a four-way junction at 1.6 A resolution: new insights into solvent interactions.,Chakraborty A, Mandal PK, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1169-74., doi: 10.1107/S1744309112034926. Epub 2012 Sep 25. PMID:23027741<ref>PMID:23027741</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
== References == | |||
<references/> | |||
== | __TOC__ | ||
</StructureSection> | |||
[[Category: Chakraborty, A | [[Category: Chakraborty, A]] | ||
[[Category: Gautham, N | [[Category: Gautham, N]] | ||
[[Category: Mandal, P K | [[Category: Mandal, P K]] | ||
[[Category: Dna]] | [[Category: Dna]] | ||
[[Category: Dna four-way junction]] | [[Category: Dna four-way junction]] | ||
[[Category: Sodium ion]] | [[Category: Sodium ion]] | ||
Revision as of 18:36, 9 December 2014
Crystal Structure of d(CCGGGACCGG)4 as a four-way junction at 1.6 angstrom resolutionCrystal Structure of d(CCGGGACCGG)4 as a four-way junction at 1.6 angstrom resolution
Structural highlights
Publication Abstract from PubMedThe crystal structure of the decamer sequence d(CCGGGACCGG)(4) has previously been reported at 2.16 A resolution as a four-way junction. Here, the structure of this sequence is reported at the significantly higher resolution of 1.6 A, which is the highest resolution reported for a four-way junction. This allowed the unambiguous identification of an extensive hydration network with distinct patterns and solvent-mediated interactions that shed new light on the role of water in the formation and stabilization of junction structures. Structure of d(CCGGGACCGG)(4) as a four-way junction at 1.6 A resolution: new insights into solvent interactions.,Chakraborty A, Mandal PK, Gautham N Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Oct 1;68(Pt 10):1169-74., doi: 10.1107/S1744309112034926. Epub 2012 Sep 25. PMID:23027741[1] From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine. References
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